Mepronil

Mepronil

SCHEMBL6429840

Cc1ccccc1C(=O)Nc1cccc(OC(C)C)c1.Cl[Hg]Cl

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KCNK3 O14649 5/20 0.61
KCNK9 Q9NPC2 5/20 0.61
KMT2A Q03164 3/20 0.61
POLB P06746 2/20 0.61
F2R P25116 2/20 0.58
SMN1; SMN2 Q16637 3/20 0.58
ALDH1A1 P00352 2/20 0.58
MEN1 O00255 2/20 0.56
HPGD P15428 1/20 0.56
RAB9A P51151 4/20 0.54
PKM P14618 1/20 0.54
MAPT P10636 2/20 0.53
BRAF P15056 1/20 0.53
LMNA P02545 1/20 0.53
ALOX12 P18054 1/20 0.53
NPC1 O15118 3/20 0.52
TP53 P04637 1/20 0.52
THRB P10828 1/20 0.52
DHODH Q02127 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Mepronil SCHEMBL18447 0.95 KCNK3 (0.67) KCNK3KCNK9KMT2APOLBF2R
Mepronil SCHEMBL20522512 0.95 KCNK3 (0.67) KCNK3KCNK9KMT2APOLBF2R
Mepronil SCHEMBL30731287 0.95 KCNK3 (0.67) KCNK3KCNK9KMT2APOLBF2R
Mepronil SCHEMBL29453871 0.95 KCNK3 (0.67) KCNK3KCNK9KMT2APOLBF2R
Flutolanil SCHEMBL18222334 0.84 KCNK3 (0.59) KCNK3KCNK9KMT2APOLBF2R
SCHEMBL11599863 0.84 F2R (0.60) KCNK3KCNK9KMT2APOLBF2R
SCHEMBL11587410 0.83 KMT2A (0.71) KCNK3KCNK9KMT2AF2RSMN1; SMN2
SCHEMBL4436642 0.82 KCNK3 (0.77) KCNK3KCNK9KMT2APOLBSMN1; SMN2
Mepronil SCHEMBL23303508 0.81 TSHR (0.60) KCNK3KCNK9KMT2APOLBF2R
SCHEMBL11668137 0.80 KCNK3 (0.84) KCNK3KCNK9KMT2APOLBF2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1596657-A2 FUNGICIDE COMPOSITION COMPRISING FENAMIDONE AND HYMEXAZOL Bayer CropScience S.A. (FR) 2005-11-23 EP disclosed
WO-2004073401-A2 FUNGICIDE COMPOSITION COMPRISING FENAMIDONE AND HYMEXAZOL BAYER CROPSCIENCE SA (FR) 2004-09-02 WO disclosed