Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 5/20 | 0.67 |
| ▸ | KCNK9 | Q9NPC2 | 5/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.67 |
| ▸ | POLB | P06746 | 2/20 | 0.67 |
| ▸ | F2R | P25116 | 2/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 5/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 3/20 | 0.57 |
| ▸ | BRAF | P15056 | 1/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | PLAU | P00749 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Mepronil SCHEMBL18447 | 1.00 | KCNK3 (0.67) | KCNK3KCNK9KMT2APOLBF2R | |
| Mepronil SCHEMBL30731287 | 1.00 | KCNK3 (0.67) | KCNK3KCNK9KMT2APOLBF2R | |
| Mepronil SCHEMBL29453871 | 1.00 | KCNK3 (0.67) | KCNK3KCNK9KMT2APOLBF2R | |
| Mepronil SCHEMBL6429840 | 0.95 | KCNK3 (0.61) | KCNK3KCNK9KMT2APOLBF2R | |
| Flutolanil SCHEMBL18222334 | 0.89 | KCNK3 (0.59) | KCNK3KCNK9KMT2APOLBF2R | |
| SCHEMBL11599863 | 0.88 | F2R (0.60) | KCNK3KCNK9KMT2APOLBF2R | |
| SCHEMBL4436642 | 0.87 | KCNK3 (0.77) | KCNK3KCNK9KMT2APOLBSMN1; SMN2 | |
| SCHEMBL11668137 | 0.85 | KCNK3 (0.84) | KCNK3KCNK9KMT2APOLBF2R | |
| SCHEMBL11587410 | 0.84 | KMT2A (0.71) | KCNK3KCNK9KMT2AF2RSMN1; SMN2 | |
| SCHEMBL7667058 | 0.84 | FADS1 (0.69) | KCNK3KCNK9KMT2ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3609579-A1 | ANTIMICROBIAL COMPOUNDS FROM THE GENUS DELFTIA | Ministry Of Health, State Of Israel (IL) | 2020-02-19 | — | — | EP | disclosed |
| WO-2018178986-A1 | ANTIMICROBIAL COMPOUNDS FROM THE GENUS DELFTIA | MINISTRY OF HEALTH, STATE OF ISRAEL (IL) | 2018-10-04 | — | — | WO | disclosed |