SCHEMBL115875

SCHEMBL115875

OCC(CO)(CO)NCC(O)CNC(CO)(CO)CO

nearest known ligand 0.50

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 1/20 0.43
KDM4E B2RXH2 2/20 0.33
HSD17B10 Q99714 2/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
ALDH1A1 P00352 2/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7608129 0.89 RAB9A (0.41) RAB9AKDM4EHSD17B10MEN1KMT2A
SCHEMBL14660942 0.85 RAB9A (0.39) RAB9AKDM4EHSD17B10MEN1KMT2A
SCHEMBL116946 0.85 RAB9A (0.36) RAB9AKDM4EHSD17B10MEN1KMT2A
SCHEMBL28410443 0.82 RAB9A (0.36) RAB9A
SCHEMBL8276605 0.81 RAB9A (0.37) RAB9AKDM4EHSD17B10MEN1KMT2A
SCHEMBL21787548 0.79 RAB9A (0.34) RAB9A
SCHEMBL12227939 0.79 RAB9A (0.36) RAB9AKDM4EHSD17B10MEN1KMT2A
SCHEMBL6213345 0.78 TDP1 (0.38) RAB9AALDH1A1
SCHEMBL23859620 0.78 RAB9A (0.36) RAB9AKDM4EHSD17B10ALDH1A1SMN1; SMN2
SCHEMBL167450 0.78 RAB9A (0.36) RAB9AKDM4EHSD17B10ALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2424833-B1 POLYHYDROXY-DIAMINES AS MULTI-FUNCTIONAL ADDITIVES FOR PAINTS, COATINGS AND EXPOXIES ANGUS CHEMICAL (US) 2015-07-29 EP claimed
US-8702859-B2 Polyhydroxy-diamines as multi-functional additives for paints, coatings and epoxies DOW GLOBAL TECHNOLOGIES LLC (US) 2014-04-22 US claimed
EP-2424833-A1 POLYHYDROXY-DIAMINES AS MULTI-FUNCTIONAL ADDITIVES FOR PAINTS, COATINGS AND EXPOXIES Dow Global Technologies LLC (US) 2012-03-07 EP claimed
US-20120035298-A1 POLYHYDROXY-DIAMINES AS MULTI-FUNCTIONAL ADDITIVES FOR PAINTS, COATINGS AND EPOXIES ADVANCION CORPORATION 2012-02-09 US claimed
WO-2010126962-A1 POLYHYDROXY-DIAMINES AS MULTI-FUNCTIONAL ADDITIVES FOR PAINTS, COATINGS AND EXPOXIES DOW GLOBAL TECHNOLOGIES INC. (US) 2010-11-04 WO claimed
EP-2348360-B1 Photoresist comprising nitrogen-containing compound ROHM & HAAS ELECT MAT (US) 2017-09-27 EP disclosed
EP-2424833-B1 POLYHYDROXY-DIAMINES AS MULTI-FUNCTIONAL ADDITIVES FOR PAINTS, COATINGS AND EXPOXIES ANGUS CHEMICAL (US) 2015-07-29 EP disclosed
US-8877979-B2 Polyhydroxy-diamines as multi-functional additives for paints, coatings and epoxies DOW GLOBAL TECHNOLOGIES LLC (US) 2014-11-04 US disclosed
US-8790456-B2 Polyhydroxy-diamines as multi-functional additives for paints, coatings and epoxies ANGUS CHEMICAL COMPANY 2014-07-29 US disclosed
US-20140187678-A1 POLYHYDROXY-DIAMINES AS MULTI-FUNCTIONAL ADDITIVES FOR PAINTS, COATINGS AND EPOXIES ANGUS CHEMICAL COMPANY (US) 2014-07-03 US disclosed
US-20140187820-A1 POLYHYDROXY-DIAMINES AS MULTI-FUNCTIONAL ADDITIVES FOR PAINTS, COATINGS AND EPOXIES ANGUS CHEMICAL COMPANY (US) 2014-07-03 US disclosed
US-8702859-B2 Polyhydroxy-diamines as multi-functional additives for paints, coatings and epoxies DOW GLOBAL TECHNOLOGIES LLC (US) 2014-04-22 US disclosed
WO-2011068858-A1 ADDUCTS BASED ON DIVINYLARENE OXIDES DOW GLOBAL TECHNOLOGIES LLC (US) 2011-06-09 WO disclosed
US-20110137076-A1 Biological Buffers with Wide Buffering Ranges TPAT IP LLC 2011-06-09 US disclosed
US-7939659-B2 Biological buffers with wide buffering ranges TPAT IP LLC 2011-05-10 US disclosed
US-7851652-B2 Biological buffers with wide buffering ranges TPAT IP LLC 2010-12-14 US disclosed
WO-2010126962-A1 POLYHYDROXY-DIAMINES AS MULTI-FUNCTIONAL ADDITIVES FOR PAINTS, COATINGS AND EXPOXIES DOW GLOBAL TECHNOLOGIES INC. (US) 2010-11-04 WO disclosed
US-20100190993-A1 Biological Buffers with Wide Buffering Ranges TPAT IP LLC 2010-07-29 US disclosed
US-20100099868-A1 Biological Buffers with Wide Buffering Ranges TPAT IP LLC 2010-04-22 US disclosed
US-20090264651-A1 Biological Buffers with Wide Buffering Ranges TPAT IP LLC 2009-10-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090264651-A1 Biological Buffers with Wide Buffering Ranges PEF1, SLC7A1, PLPBP RAB9A 597/4885KDM4E 2858/4885HSD17B10 4309/4885
US-20120035298-A1 POLYHYDROXY-DIAMINES AS MULTI-FUNCTIONAL ADDITIVES FOR PAINTS, COATINGS AND EPOXIES AOC1, DAO, DDO RAB9A 2680/4885KDM4E 594/4885HSD17B10 1855/4885
US-20100099868-A1 Biological Buffers with Wide Buffering Ranges PEF1, SLC7A1, PLPBP RAB9A 597/4885KDM4E 2858/4885HSD17B10 4309/4885
US-20100190993-A1 Biological Buffers with Wide Buffering Ranges PEF1, SLC7A1, PLPBP RAB9A 597/4885KDM4E 2858/4885HSD17B10 4309/4885
US-20110137076-A1 Biological Buffers with Wide Buffering Ranges PEF1, SLC7A1, PLPBP RAB9A 597/4885KDM4E 2858/4885HSD17B10 4309/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.