SCHEMBL11587776

SCHEMBL11587776

Cc1cn([C@H]2C[C@H](O)[C@@H](COP(=O)(Oc3ccc([N+](=O)[O-])cc3)OP(=O)(O)O)O2)c(=O)[nH]c1=O

nearest known ligand 0.65

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TYMS P04818 4/20 0.65
POLB P06746 1/20 0.63
TK1 P04183 3/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20582548 0.95 TYMS (0.63) TYMSPOLBTK1
SCHEMBL8170305 0.92 TYMS (0.63) TYMSPOLBTK1
SCHEMBL3063249 0.91 TYMS (0.68) TYMSPOLBTK1
SCHEMBL8428624 0.91 TYMS (0.68) TYMSPOLBTK1
Ammonia Solution, Strong SCHEMBL8170309 0.91 TYMS (0.67) TYMSPOLBTK1
SCHEMBL2057388 0.90 TYMS (0.64) TYMSPOLBTK1
SCHEMBL21003255 0.89 TYMS (0.65) TYMSPOLBTK1
Doxribtimine SCHEMBL20797965 0.86 TYMS (0.63) TYMSPOLBTK1
Thymidine Monophosphate SCHEMBL20797966 0.86 TYMS (0.75) TYMSPOLBTK1
SCHEMBL27324821 0.86 POLB (0.80) TYMSPOLBTK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4124724-A Crystalline caffeic acid derivatives and compositions and method for treating snakebite AGORO JOHN W 1978-11-07 US disclosed