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Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL8170309

Cc1cn([C@H]2C[C@H](O)[C@@H](COP(=O)(O)Oc3ccc([N+](=O)[O-])cc3)O2)c(=O)[nH]c1=O.N

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ TYMS P04818 4/20 0.67
▸ POLB P06746 1/20 0.61
▸ TK1 P04183 3/20 0.54
▸ P2RY6 Q15077 1/20 0.53
▸ P2RY14 Q15391 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3063249 0.99 TYMS (0.68) TYMSPOLBTK1
SCHEMBL8428624 0.99 TYMS (0.68) TYMSPOLBTK1
SCHEMBL2057388 0.94 TYMS (0.64) TYMSPOLBTK1P2RY6P2RY14
SCHEMBL20582548 0.92 TYMS (0.63) TYMSPOLBTK1P2RY6P2RY14
SCHEMBL11587776 0.91 TYMS (0.65) TYMSPOLBTK1
SCHEMBL21003255 0.90 TYMS (0.65) TYMSPOLBTK1
SCHEMBL5832481 0.90 TYMS (0.60) TYMSPOLBTK1
SCHEMBL5832477 0.90 TYMS (0.60) TYMSPOLBTK1
SCHEMBL8170305 0.89 TYMS (0.63) TYMSPOLBTK1
Thymidine Monophosphate SCHEMBL20797966 0.88 TYMS (0.75) TYMSPOLBTK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1045925-A1 ENZYME-SPECIFIC CLEAVABLE POLYNUCLEOTIDE SUBSTRATE AND ASSAY METHOD MINNESOTA MINING AND MANUFACTURING COMPANY (US) 2000-10-25 — — EP disclosed
WO-1999035288-A1 ENZYME-SPECIFIC CLEAVABLE POLYNUCLEOTIDE SUBSTRATE AND ASSAY METHOD MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1999-07-15 — — WO disclosed