SCHEMBL3063249

SCHEMBL3063249

Cc1cn([C@H]2CC(O)[C@@H](COP(=O)(O)Oc3ccc([N+](=O)[O-])cc3)O2)c(=O)[nH]c1=O

nearest known ligand 0.68

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TYMS P04818 4/20 0.68
POLB P06746 1/20 0.61
TK1 P04183 3/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8428624 1.00 TYMS (0.68) TYMSPOLBTK1
Ammonia Solution, Strong SCHEMBL8170309 0.99 TYMS (0.67) TYMSPOLBTK1
SCHEMBL2057388 0.95 TYMS (0.64) TYMSPOLBTK1
SCHEMBL20582548 0.92 TYMS (0.63) TYMSPOLBTK1
SCHEMBL11587776 0.91 TYMS (0.65) TYMSPOLBTK1
SCHEMBL21003255 0.91 TYMS (0.65) TYMSPOLBTK1
SCHEMBL5832481 0.91 TYMS (0.60) TYMSPOLBTK1
SCHEMBL5832477 0.91 TYMS (0.60) TYMSPOLBTK1
SCHEMBL8170305 0.90 TYMS (0.63) TYMSPOLBTK1
Doxribtimine SCHEMBL20797965 0.88 TYMS (0.63) TYMSPOLBTK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100267044-A1 GENETICALLY ENGINEERED BIOLOGICAL INDICATOR FRANCISKOVICH PHILLIP P 2010-10-21 US claimed
EP-2084294-A2 STERILIZATION INDICATOR American Sterilizer Company (US) 2009-08-05 EP claimed
EP-2084293-A2 GENETICALLY ENGINEERED BIOLOGICAL INDICATOR American Sterilizer Company (US) 2009-08-05 EP claimed
WO-2008082728-A2 STERILIZATION INDICATOR AMERICAN STERILIZER COMPANY (US) 2008-07-10 WO claimed
WO-2008079469-A2 GENETICALLY ENGINEERED BIOLOGICAL INDICATOR AMERICAN STERILIZER COMPANY (US) 2008-07-03 WO claimed
CN-112930397-B ENPP1 polypeptides and methods of use thereof 耶鲁大学 2025-05-09 CN disclosed
US-12024700-B2 Biological disinfection or sterilization indicator TERRAGENE LLC (US) 2024-07-02 US disclosed
CN-113993993-A ENPP1 polypeptides and methods of use thereof 耶鲁大学 2022-01-28 CN disclosed
US-20210179998-A1 BIOLOGICAL DISINFECTION OR STERILIZATION INDICATOR TERRAGENE LLC (US) 2021-06-17 US disclosed
CN-112930397-A ENPP1 polypeptides and methods of use thereof 耶鲁大学 2021-06-08 CN disclosed
US-11001799-B2 Biological disinfection or sterilization indicator TERRAGENE LLC (US) 2021-05-11 US disclosed
US-20200123492-A1 BIOLOGICAL DISINFECTION OR STERILIZATION INDICATOR TERRAGENE LLC 2020-04-23 US disclosed
EP-2643471-A1 METHODS AND COMPOSITIONS TO DETECT A BIOLOGICAL ACTIVITY 3M Innovative Properties Company (US) 2013-10-02 EP disclosed
US-20130230876-A1 METHODS AND COMPOSITIONS TO DETECT A BIOLOGICAL ACTIVITY 3M INNOVATIVE PROPERTIES COMPANY (US) 2013-09-05 US disclosed
WO-2012071131-A1 METHODS AND COMPOSITIONS TO DETECT A BIOLOGICAL ACTIVITY 3M INNOVATIVE PROPERTIES COMPANY (US) 2012-05-31 WO disclosed
EP-0371682-B1 Rapid method for determining efficacy of a sterilization cycle and rapid read-out biological indicator MINNESOTA MINING & MFG (US) 1996-05-22 EP disclosed
US-5418167-A Sterilization indicator MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-05-23 US disclosed
US-5252484-A Determination of efficiency of sterilization cycle MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-10-12 US disclosed
US-5223401-A Colorimetric analysis; substrate system producing detectable enzyme-modified product MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1993-06-29 US disclosed
US-5073488-A Using active enzyme MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1991-12-17 US disclosed