Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.35 |
| ▸ | MDM4 | O15151 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.35 |
| ▸ | MMP12 | P39900 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 4/20 | 0.33 |
| ▸ | CA2 | P00918 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TNF | P01375 | 1/20 | 0.32 |
| ▸ | TACR2 | P21452 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11590064 | 0.85 | MAPK1 (0.50) | MAPK1TP53MDM2MMP12L3MBTL1 | |
| SCHEMBL11591229 | 0.84 | MAPK1 (0.34) | MAPK1MMP12L3MBTL1CA1CA2 | |
| SCHEMBL28315418 | 0.77 | FGF1 (0.41) | CA1CA2LMNAMAPTTNF | |
| SCHEMBL9472134 | 0.76 | MAPK1 (0.54) | MAPK1TP53MDM2MMP12L3MBTL1 | |
| SCHEMBL11193105 | 0.74 | LMNA (0.43) | TP53MDM2MDM4HSP90AA1HSP90AB1 | |
| SCHEMBL11170170 | 0.74 | MAPK1 (0.65) | MAPK1MMP12L3MBTL1POLBTACR2 | |
| SCHEMBL11170361 | 0.72 | MAPK1 (0.50) | MAPK1TP53MDM2MDM4HSP90AA1 | |
| SCHEMBL9472679 | 0.72 | TNF (0.41) | MAPK1TP53MDM2MDM4HSP90AA1 | |
| SCHEMBL8720284 | 0.71 | CA1 (0.49) | CA1CA2TACR2 | |
| SCHEMBL14410762 | 0.71 | FGF1 (0.45) | L3MBTL1CA1CA2LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4101536-A | IMMUNOADJUVANT, ANTITUMOR | DAIICHI SEIYAKU CO., LTD. (JP) | 1978-07-18 | — | — | US | disclosed |