Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | GSK3B | P49841 | 2/20 | 0.48 |
| ▸ | GSK3A | P49840 | 1/20 | 0.48 |
| ▸ | CCR6 | P51684 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9858506 | 0.86 | GSK3A (0.65) | CYP3A4ALDH1A1TSHRTDP1GSK3B | |
| 4,4'-Methylenedianiline SCHEMBL15105282 | 0.78 | CYP3A4 (1.00) | CYP3A4ALDH1A1TSHRTDP1CA12 | |
| SCHEMBL6362775 | 0.78 | CYP3A4 (1.00) | CYP3A4ALDH1A1TSHRTDP1CA12 | |
| SCHEMBL1304762 | 0.78 | CYP3A4 (1.00) | CYP3A4ALDH1A1TSHRTDP1CA12 | |
| 4,4'-Methylenedianiline SCHEMBL28001 | 0.78 | CYP3A4 (1.00) | CYP3A4ALDH1A1TSHRTDP1CA12 | |
| SCHEMBL8094139 | 0.78 | CYP3A4 (1.00) | CYP3A4ALDH1A1TSHRTDP1CA12 | |
| SCHEMBL3482770 | 0.78 | CYP3A4 (1.00) | CYP3A4ALDH1A1TSHRTDP1CA12 | |
| SCHEMBL27941155 | 0.77 | CA2 (0.46) | ALDH1A1TSHRCA1CA2GFER | |
| Diphenylmethane SCHEMBL25292606 | 0.77 | CALM1 (0.57) | ALDH1A1GSK3BGSK3ACCR6MGLL | |
| Diphenylmethane SCHEMBL7026541 | 0.77 | CALM1 (0.57) | ALDH1A1GSK3BGSK3ACCR6MGLL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4110294-A | POLYIMIDES | CIBA-GEIGY CORPORATION (US) | 1978-08-29 | — | — | US | disclosed |
| US-4105646-A | α,β-Unsaturated schiff-base chain extension reactions for high temperature polymers | CIBA-GEIGY CORPORATION (US) | 1978-08-08 | — | — | US | disclosed |
| US-3979350-A | MOLDING MATERIALS | CIBA-GEIGY CORPORATION (US) | 1976-09-07 | — | — | US | disclosed |