Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.69 |
| ▸ | NR3C1 | P04150 | 5/20 | 0.69 |
| ▸ | MEN1 | O00255 | 3/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.69 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.69 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.69 |
| ▸ | MAPT | P10636 | 1/20 | 0.69 |
| ▸ | PGR | P06401 | 4/20 | 0.68 |
| ▸ | SHBG | P04278 | 4/20 | 0.68 |
| ▸ | AR | P10275 | 3/20 | 0.68 |
| ▸ | ESR1 | P03372 | 3/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.68 |
| ▸ | TSHR | P16473 | 2/20 | 0.68 |
| ▸ | THRB | P10828 | 1/20 | 0.68 |
| ▸ | CYP19A1 | P11511 | 5/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.61 |
| ▸ | ABCB11 | O95342 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.61 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11591833 | 1.00 | LMNA (0.69) | LMNANR3C1MEN1KMT2ACYP2C19 | |
| SCHEMBL11135754 | 0.88 | LMNA (0.67) | LMNANR3C1MEN1KMT2ACYP2C19 | |
| Dimethisterone Anhydrous SCHEMBL11650549 | 0.88 | NR3C1 (0.67) | LMNANR3C1MEN1KMT2ACYP2C19 | |
| Dimethisterone Anhydrous SCHEMBL9005165 | 0.88 | NR3C1 (0.67) | LMNANR3C1MEN1KMT2ACYP2C19 | |
| Dimethisterone Anhydrous SCHEMBL3978311 | 0.88 | NR3C1 (0.67) | LMNANR3C1MEN1KMT2ACYP2C19 | |
| Dimethisterone Anhydrous SCHEMBL4271134 | 0.88 | NR3C1 (0.67) | LMNANR3C1MEN1KMT2ACYP2C19 | |
| Dimethisterone Anhydrous SCHEMBL146840 | 0.88 | NR3C1 (0.67) | LMNANR3C1MEN1KMT2ACYP2C19 | |
| Dimethisterone Anhydrous SCHEMBL1649077 | 0.87 | NR3C1 (0.66) | LMNANR3C1MEN1KMT2ACYP2C19 | |
| Dimethisterone Anhydrous SCHEMBL11741246 | 0.87 | NR3C1 (0.66) | LMNANR3C1MEN1KMT2ACYP2C19 | |
| Dimethisterone Anhydrous SCHEMBL11741255 | 0.87 | NR3C1 (0.66) | LMNANR3C1MEN1KMT2ACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4100027-A | Process for the preparation of 4-androstene-3,17-dione derivatives | SCHERING AKTIENGESELLSCHAFT (DE) | 1978-07-11 | — | — | US | disclosed |