Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.67 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.67 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.67 |
| ▸ | AR | P10275 | 2/20 | 0.67 |
| ▸ | TSHR | P16473 | 2/20 | 0.67 |
| ▸ | ESR1 | P03372 | 2/20 | 0.67 |
| ▸ | SHBG | P04278 | 2/20 | 0.67 |
| ▸ | PGR | P06401 | 2/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.67 |
| ▸ | THRB | P10828 | 1/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.67 |
| ▸ | CYP19A1 | P11511 | 9/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11591827 | 0.88 | LMNA (0.69) | LMNACYP2C19HIF1ANR3C1AR | |
| SCHEMBL11591833 | 0.88 | LMNA (0.69) | LMNACYP2C19HIF1ANR3C1AR | |
| SCHEMBL8082577 | 0.82 | CYP19A1 (0.57) | LMNACYP2C19HIF1ANR3C1AR | |
| SCHEMBL11510735 | 0.82 | LMNA (0.78) | LMNACYP2C19HIF1ANR3C1AR | |
| SCHEMBL11510737 | 0.82 | LMNA (0.78) | LMNACYP2C19HIF1ANR3C1AR | |
| Ethisterone SCHEMBL16864523 | 0.80 | LMNA (1.00) | LMNACYP2C19HIF1ANR3C1AR | |
| Ethisterone SCHEMBL24475 | 0.80 | LMNA (1.00) | LMNACYP2C19HIF1ANR3C1AR | |
| Ethisterone SCHEMBL780055 | 0.80 | LMNA (1.00) | LMNACYP2C19HIF1ANR3C1AR | |
| Ethisterone SCHEMBL16691330 | 0.80 | LMNA (1.00) | LMNACYP2C19HIF1ANR3C1AR | |
| Ethisterone SCHEMBL12417537 | 0.80 | LMNA (1.00) | LMNACYP2C19HIF1ANR3C1AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4383947-A | Introduction of a fluorine atom | THE UPJOHN COMPANY (US) | 1983-05-17 | — | — | US | disclosed |