Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.50 |
| ▸ | THRA | P10827 | 6/20 | 0.46 |
| ▸ | THRB | P10828 | 6/20 | 0.46 |
| ▸ | RECQL | P46063 | 6/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23978973 | 0.87 | ESR1 (0.47) | ESR1ESR2THRATHRBRECQL | |
| SCHEMBL5950377 | 0.83 | ESR1 (0.55) | ESR1ESR2RECQLALOX15KDM4E | |
| SCHEMBL22599093 | 0.82 | ESR1 (0.55) | ESR1ESR2THRATHRBRECQL | |
| SCHEMBL5168806 | 0.82 | GABRA1 (0.63) | ESR1THRATHRBRECQLALOX15 | |
| SCHEMBL4784165 | 0.81 | ESR1 (0.68) | ESR1ESR2HSD17B10HIF1ACYP3A4 | |
| SCHEMBL3152462 | 0.80 | GAA (0.62) | RECQLALOX15KDM4ETDP1HSD17B10 | |
| SCHEMBL10070163 | 0.80 | ALOX15 (0.66) | ESR1ESR2RECQLALOX15KDM4E | |
| SCHEMBL11581325 | 0.79 | ALOX15 (0.55) | ESR1THRATHRBRECQLALOX15 | |
| SCHEMBL16973200 | 0.78 | ESR1 (0.49) | ESR1ESR2MAPK1POLBCYP2D6 | |
| SCHEMBL12949905 | 0.77 | THRA (0.51) | ESR1THRATHRBRECQLALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4101511-A | THERMAL AND PHOTOCHEMICAL STABILIZERS FOR HYDROCARBON POLYMERS | EXXON RESEARCH & ENGINEERING CO. (US) | 1978-07-18 | — | — | US | disclosed |
| US-4032510-A | ENDCAPPED BISPHENOL DERIVATIVES | EXXON RESEARCH AND ENGINEERING COMPANY (US) | 1977-06-28 | — | — | US | disclosed |