Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3A | P49840 | 1/20 | 0.45 |
| ▸ | GSK3B | P49841 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TNF | P01375 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11714254 | 0.86 | TNF (0.57) | FAAHALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL11712403 | 0.83 | FABP4 (0.54) | GSK3AGSK3BMEN1KMT2ATSHR | |
| SCHEMBL11134221 | 0.83 | HTR7 (0.47) | FAAHKDM4ETP53LMNATNF | |
| SCHEMBL11133032 | 0.83 | HTR7 (0.47) | FAAHKDM4ETP53LMNATNF | |
| SCHEMBL11512747 | 0.82 | KDM4E (0.57) | FAAHALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL11127880 | 0.81 | FAAH (0.56) | FAAHALDH1A1MEN1RAB9AKMT2A | |
| SCHEMBL24703577 | 0.80 | TSHR (0.62) | FAAHALDH1A1TSHRTP53KAT2B | |
| SCHEMBL8413938 | 0.79 | TSHR (0.46) | GSK3AGSK3BALDH1A1MEN1KMT2A | |
| SCHEMBL11630854 | 0.77 | GSK3A (0.55) | GSK3AGSK3BALDH1A1RAB9ATSHR | |
| SCHEMBL11714057 | 0.77 | MAPT (0.54) | GSK3AGSK3BALDH1A1TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4108841-A | FROM DIACIDS CONTAINING HETEROCYCLIC RINGS | CIBA-GEIGY CORPORATION (US) | 1978-08-22 | — | — | US | disclosed |