Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.65 |
| ▸ | MEN1 | O00255 | 5/20 | 0.65 |
| ▸ | PKM | P14618 | 1/20 | 0.65 |
| ▸ | DHODH | Q02127 | 1/20 | 0.58 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 4/20 | 0.53 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | CASP3 | P42574 | 1/20 | 0.53 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.53 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6848585 | 0.91 | NPC1 (0.54) | KMT2AMEN1PKMDHODHPBRM1 | |
| SCHEMBL11086880 | 0.87 | HSD17B10 (0.62) | KMT2AMEN1PKMNPC1RAB9A | |
| SCHEMBL6847188 | 0.86 | NPC1 (0.53) | KMT2AMEN1PKMDHODHPBRM1 | |
| SCHEMBL2058331 | 0.85 | ALDH1A1 (0.68) | KMT2AMEN1PKMDHODHNPC1 | |
| SCHEMBL6841680 | 0.84 | ALDH1A1 (0.72) | KMT2AMEN1NPC1RAB9AALDH1A1 | |
| SCHEMBL7832216 | 0.81 | MEN1 (0.68) | KMT2AMEN1PKMDHODHNPC1 | |
| SCHEMBL11594362 | 0.80 | CYP1A2 (0.68) | KMT2AMEN1PBRM1NPC1RAB9A | |
| SCHEMBL11405554 | 0.80 | LMNA (0.76) | KMT2AMEN1PKMDHODHNPC1 | |
| SCHEMBL4669122 | 0.80 | LMNA (0.76) | KMT2AMEN1PKMDHODHNPC1 | |
| SCHEMBL15183709 | 0.80 | KMT2A (0.77) | KMT2AMEN1PKMDHODHNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6767983-B1 | SILICONE RESINS HAVING SPECIFIED TRIORGANOSILYL GROUP LINKED TO ALL OR PART OF ENDS OF BACKBONE CHAIN OF POLYSILSESQUIOXANES; PHOTORESISTS | NIPPON STEEL CHEMICAL CO., LTD. (JP) | 2004-07-27 | — | — | US | disclosed |