Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 3/20 | 0.40 |
| ▸ | CCR1 | P32246 | 1/20 | 0.40 |
| ▸ | CCR5 | P51681 | 1/20 | 0.40 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.40 |
| ▸ | ADCY1 | Q08828 | 5/20 | 0.37 |
| ▸ | CNR1 | P21554 | 6/20 | 0.35 |
| ▸ | CNR2 | P34972 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ACAT1 | P24752 | 1/20 | 0.35 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.35 |
| ▸ | ADCY8 | P40145 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11595197 | 0.78 | CCR2 (0.39) | CCR2CCR1CCR5CXCR4ADCY1 | |
| SCHEMBL11595129 | 0.78 | KDM4E (0.39) | CNR1CNR2KDM4ETP53CYP3A4 | |
| SCHEMBL11596585 | 0.70 | KDM4E (0.36) | CNR1CNR2KDM4ETP53CYP3A4 | |
| SCHEMBL11596174 | 0.70 | AR (0.40) | CCR2CNR1CNR2KDM4ETP53 | |
| SCHEMBL22523022 | 0.68 | HPGD (0.43) | ADCY1KDM4ETSHRPKM | |
| SCHEMBL24043829 | 0.68 | ALDH1A1 (0.32) | ADCY1KDM4ETP53 | |
| SCHEMBL11593178 | 0.67 | TP53 (0.38) | CCR2CCR1CCR5CXCR4CNR1 | |
| SCHEMBL11540052 | 0.66 | CNR2 (0.37) | CCR2CCR1CCR5CXCR4CNR1 | |
| SCHEMBL11544529 | 0.66 | KDM4E (0.40) | CNR1CNR2KDM4ETP53CYP3A4 | |
| SCHEMBL11536828 | 0.65 | KDM4E (0.39) | CNR1CNR2KDM4ETP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4122183-A | ANTIASTHMATIC | LILLY INDUSTRIES LIMITED (GB) | 1978-10-24 | — | — | US | disclosed |