Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 1/20 | 0.51 |
| ▸ | CTSK | P43235 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 3/20 | 0.45 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.45 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.45 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.43 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 3/20 | 0.42 |
| ▸ | PPARG | P37231 | 2/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | BCL2 | P10415 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11596126 | 0.91 | CTSS (0.49) | CTSSCTSKATMITGB3ITGA2B | |
| SCHEMBL844326 | 0.89 | CTSS (0.50) | CTSSCTSKATMITGB3ITGA2B | |
| SCHEMBL11644546 | 0.89 | CTSS (0.47) | CTSSCTSKITGB3ITGA2BS1PR3 | |
| SCHEMBL844327 | 0.89 | CTSS (0.50) | CTSSCTSKATMITGB3ITGA2B | |
| SCHEMBL11591555 | 0.89 | CTSS (0.47) | CTSSCTSKITGB3ITGA2BS1PR3 | |
| SCHEMBL3811492 | 0.88 | ITGB3 (0.51) | CTSSCTSKATMITGB3ITGA2B | |
| SCHEMBL3814568 | 0.88 | ITGB3 (0.51) | CTSSCTSKATMITGB3ITGA2B | |
| SCHEMBL3377050 | 0.87 | CTSS (0.53) | CTSSCTSKATMITGB3ITGA2B | |
| SCHEMBL3377047 | 0.87 | CTSS (0.53) | CTSSCTSKATMITGB3ITGA2B | |
| SCHEMBL4684444 | 0.86 | CTSS (0.50) | CTSSCTSKATMITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4094978-A | 3-PROPENYL DERIVATIVES OF CEPHALOSPORIN, COMPOSITIONS AND THEIR USE | SYNTEX (U.S.A.) INC. (US) | 1978-06-13 | — | — | US | disclosed |