Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.43 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11571012 | 0.94 | LTB4R2 (0.41) | SLC18A3LTB4R2CHRM2CHRM3CHRM1 | |
| SCHEMBL11341302 | 0.90 | ALDH1A1 (0.38) | LTB4R2CHRM2CHRM3CHRM1KMT2A | |
| SCHEMBL11346998 | 0.88 | KDM4E (0.34) | SLC18A3LTB4R2KMT2ASIGMAR1NPC1 | |
| SCHEMBL11571013 | 0.85 | SLC18A3 (0.44) | SLC18A3CHRM2CHRM3CHRM1SIGMAR1 | |
| SCHEMBL11330427 | 0.82 | SLC18A3 (0.46) | SLC18A3CHRM2CHRM3L3MBTL1SIGMAR1 | |
| SCHEMBL11454736 | 0.82 | LTB4R2 (0.38) | LTB4R2CHRM2CHRM3CHRM1KMT2A | |
| SCHEMBL11465401 | 0.81 | ALDH1A1 (0.43) | LTB4R2CHRM2CHRM3KMT2ASIGMAR1 | |
| SCHEMBL11595372 | 0.81 | SLC18A3 (0.50) | SLC18A3CHRM2CHRM3CHRM1KMT2A | |
| SCHEMBL11572452 | 0.81 | LTB4R2 (0.34) | LTB4R2KMT2ASIGMAR1NPC1RAB9A | |
| SCHEMBL11330981 | 0.78 | SLC18A3 (0.45) | SLC18A3CHRM2CHRM3KMT2ASIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE30837-E | ANTIDEPRESSANTS | THE UPJOHN COMPANY (US) | 1981-12-29 | — | — | US | disclosed |
| US-4169156-A | ANTIDEPRESSANTS | THE UPJOHN COMPANY (US) | 1979-09-25 | — | — | US | disclosed |