Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | CA12 | O43570 | 2/20 | 0.52 |
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | CA7 | P43166 | 2/20 | 0.52 |
| ▸ | CA9 | Q16790 | 2/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | PPARA | Q07869 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28732226 | 0.89 | HSP90AB1 (0.69) | HSP90AB1ALDH1A1CA12CA1CA2 | |
| SCHEMBL1576999 | 0.85 | CSNK2A1 (0.53) | HSP90AB1ALDH1A1CA12CA1CA2 | |
| SCHEMBL8962217 | 0.85 | CDC25A (0.53) | HSP90AB1ALDH1A1TSHRMAPTKDM4E | |
| SCHEMBL988145 | 0.83 | SMN1; SMN2 (0.48) | HSP90AB1ALDH1A1PPARAMAPTKDM4E | |
| SCHEMBL13434942 | 0.83 | MEN1 (0.60) | HSP90AB1ALDH1A1MAPTGAAKDM4E | |
| SCHEMBL22563026 | 0.82 | ALDH1A1 (0.48) | HSP90AB1ALDH1A1CA12CA1CA2 | |
| SCHEMBL21839460 | 0.82 | HTT (0.60) | ALDH1A1PPARAMAPTKDM4EHTT | |
| SCHEMBL11589494 | 0.81 | ALDH1A1 (0.52) | ALDH1A1CA12CA1CA2CA7 | |
| SCHEMBL11455991 | 0.81 | ALDH1A1 (0.52) | ALDH1A1CA12CA1CA2CA7 | |
| SCHEMBL14360615 | 0.81 | ALDH1A1 (0.47) | HSP90AB1ALDH1A1MAPTKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4072753-A | DERMATITIS, MULTIPLE SCLEROSIS, BENZANILIDES | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JA) | 1978-02-07 | — | — | US | disclosed |
| US-4032635-A | BENZANILIDE DERIVATIVES | ZAIDAN HOJIN BISEIBUTSU KAGAKU KENKYU KAI (JA) | 1977-06-28 | — | — | US | disclosed |