Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC25A | P30304 | 1/20 | 0.53 |
| ▸ | CDC25B | P30305 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19328971 | 0.86 | KDM4E (0.55) | CDC25ACDC25BHSD17B10L3MBTL1POLB | |
| SCHEMBL988145 | 0.86 | SMN1; SMN2 (0.48) | L3MBTL1ATMSMN1; SMN2MAPTKDM4E | |
| SCHEMBL14360615 | 0.85 | ALDH1A1 (0.47) | L3MBTL1ATMSMN1; SMN2MAPTKDM4E | |
| SCHEMBL1576999 | 0.85 | CSNK2A1 (0.53) | HSD17B10L3MBTL1TDP1SMN1; SMN2MAPT | |
| SCHEMBL15544772 | 0.85 | MAPT (0.47) | L3MBTL1TDP1ATMSMN1; SMN2MAPT | |
| SCHEMBL8962350 | 0.85 | HPGD (0.54) | CDC25ACDC25BHSD17B10L3MBTL1POLB | |
| SCHEMBL11595459 | 0.85 | HSP90AB1 (0.55) | L3MBTL1POLBATMSMN1; SMN2MAPT | |
| Propionic Acid SCHEMBL122758 | 0.84 | KDM4E (0.56) | CDC25ACDC25BHSD17B10L3MBTL1POLB | |
| SCHEMBL31186552 | 0.83 | HSD17B10 (0.57) | CDC25ACDC25BHSD17B10L3MBTL1POLB | |
| Propane SCHEMBL8954698 | 0.83 | KDM4E (0.60) | CDC25ACDC25BHSD17B10L3MBTL1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5530130-A | DYEING PLASTICS | BAYER AKTIENGESELLSCHAFT (DE) | 1996-06-25 | — | — | US | disclosed |
| EP-0639624-A1 | Phthaloperinone dyestuffs | BAYER AG (DE) | 1995-02-22 | — | — | EP | disclosed |