SCHEMBL14360615

SCHEMBL14360615

CCC(=O)c1ccc(C(=O)O)c(CC)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.47
HPGD P15428 2/20 0.47
HTT P42858 1/20 0.47
SMN1; SMN2 Q16637 3/20 0.47
MAPT P10636 2/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
ATM Q13315 1/20 0.45
MEN1 O00255 3/20 0.43
KMT2A Q03164 3/20 0.43
GABRP O00591 1/20 0.42
GABRD O14764 1/20 0.42
GABRA1 P14867 1/20 0.42
GABRB1 P18505 1/20 0.42
GABRG2 P18507 1/20 0.42
GABRB3 P28472 1/20 0.42
GABRA5 P31644 1/20 0.42
GABRA3 P34903 1/20 0.42
GABRA2 P47869 1/20 0.42
GABRB2 P47870 1/20 0.42
GABRA4 P48169 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL277909 0.88 ALDH1A1 (0.54) ALDH1A1HPGDHTTSMN1; SMN2MAPT
SCHEMBL6272280 0.86 ALDH1A1 (0.46) ALDH1A1HTTSMN1; SMN2MAPTMEN1
SCHEMBL8962217 0.85 CDC25A (0.53) ALDH1A1HPGDHTTSMN1; SMN2MAPT
SCHEMBL3230477 0.83 AKR1C3 (0.50) ALDH1A1HTTGABRPGABRDGABRA1
SCHEMBL988145 0.83 SMN1; SMN2 (0.48) ALDH1A1HPGDHTTSMN1; SMN2MAPT
SCHEMBL11595459 0.81 HSP90AB1 (0.55) ALDH1A1HPGDHTTSMN1; SMN2MAPT
SCHEMBL10886320 0.80 ALDH1A1 (0.53) ALDH1A1HPGDHTTSMN1; SMN2MAPT
SCHEMBL2000489 0.80 RXRA (0.44) ALDH1A1MEN1KMT2AGABRPGABRD
SCHEMBL19328971 0.79 KDM4E (0.55) ALDH1A1HPGDHTTSMN1; SMN2MAPT
SCHEMBL10936584 0.79 HSD17B1 (0.54) ALDH1A1HPGDHTTSMN1; SMN2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2726051-A1 PHOTOLABILE PRO-FRAGRANCES Henkel AG & Co. KGaA (DE) 2014-05-07 EP disclosed
WO-2013000669-A1 PHOTOLABILE PRO-FRAGRANCES HENKEL AG & CO. KGAA (DE) 2013-01-03 WO disclosed