SCHEMBL11595659

SCHEMBL11595659

COc1ccc(-c2nc(-c3cc(C)c(O)c(C)c3)[nH]c2-c2ccc(OC)cc2)cc1

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMPD3 Q9NY59 3/20 0.76
NOX1 Q9Y5S8 3/20 0.71
MAPT P10636 6/20 0.64
TP53 P04637 3/20 0.64
ALOX5 P09917 3/20 0.64
MAPK13 O15264 2/20 0.57
MAPK12 P53778 2/20 0.57
MAPK11 Q15759 2/20 0.57
MAPK14 Q16539 2/20 0.57
RAF1 P04049 1/20 0.57
MEN1 O00255 4/20 0.57
ALDH1A1 P00352 4/20 0.57
HPGD P15428 4/20 0.57
KMT2A Q03164 4/20 0.57
KDM4E B2RXH2 3/20 0.57
NPSR1 Q6W5P4 2/20 0.57
CYP1A2 P05177 1/20 0.57
GLA P06280 1/20 0.57
GAA P10253 1/20 0.57
CYP2C19 P33261 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13233363 0.91 SMPD3 (0.64) SMPD3NOX1MAPTTP53ALOX5
SCHEMBL6469604 0.88 SMPD3 (0.66) SMPD3NOX1MAPTTP53ALOX5
SCHEMBL6691401 0.86 SMPD3 (1.00) SMPD3NOX1MAPTTP53ALOX5
SCHEMBL12152165 0.86 ALOX5 (0.70) SMPD3NOX1MAPTTP53ALOX5
SCHEMBL12103632 0.86 SMPD3 (0.71) SMPD3NOX1MAPTTP53ALOX5
SCHEMBL15400824 0.84 NOX1 (0.85) SMPD3NOX1MAPTTP53ALOX5
SCHEMBL8008805 0.84 NOX1 (0.85) SMPD3NOX1MAPTTP53ALOX5
SCHEMBL6469493 0.83 ALOX5 (0.67) SMPD3NOX1MAPTTP53ALOX5
SCHEMBL6467821 0.83 SMPD3 (0.71) SMPD3NOX1MAPTTP53ALOX5
SCHEMBL6467393 0.83 NOX1 (1.00) SMPD3NOX1MAPTTP53ALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8384982-B2 Display element KONICA MINOLTA HOLDINGS, INC. (JP) 2013-02-26 US disclosed
US-8049948-B2 Process for producing electrochemical display element and electrochemical display element KONICA MINOLTA HOLDINGS, INC. (JP) 2011-11-01 US disclosed
US-8014056-B2 Display element and method of driving the same KONICA MINOLTA HOLDINGS, INC. (JP) 2011-09-06 US disclosed
US-8004742-B2 Electrochromic display device KONICA MINOLTA HOLDINGS, INC. (JP) 2011-08-23 US disclosed
US-20110058244-A1 ELECTROCHROMIC DISPLAY ELEMENT KONICA MINOLTA HOLDINGS, INC. (JP) 2011-03-10 US disclosed
US-20100213813-A1 DISPLAY ELEMENT EDISON INNOVATIONS LLC 2010-08-26 US disclosed
US-20100134864-A1 PROCESS FOR PRODUCING ELECTROCHEMICAL DISPLAY ELEMENT AND ELECTROCHEMICAL DISPLAY ELEMENT KONICA MINOLTA HOLDINGS ,INC. (JP) 2010-06-03 US disclosed
US-20100091353-A1 DISPLAY ELEMENT AND METHOD OF DRIVING THE SAME KONICA MINOLTA HOLDINGS, INC. (JP) 2010-04-15 US disclosed
US-20090316249-A1 ELECTROCHROMIC DISPLAY DEVICE KONICA MINOLTA HOLDINGS, INC. (JP) 2009-12-24 US disclosed
US-7619803-B2 Electrochromic display element and full-color electrochromic display element KONICA MINOLTA HOLDINGS, INC. (JP) 2009-11-17 US disclosed
US-20090027757-A1 ELECTROCHROMIC DISPLAY ELEMENT AND FULL-COLOR ELECTROCHROMIC DISPLAY ELEMENT KONICA MINOLTA HOLDINGS, INC. (JP) 2009-01-29 US disclosed
US-4093358-A OXIDANT OF TRIARYL PYRAZOLINE INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1978-06-06 US disclosed