SCHEMBL12152165

SCHEMBL12152165

Cc1cc(-c2nc(-c3ccc(O)cc3)c(-c3ccc(O)cc3)[nH]2)cc(C)c1O

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.70
NOX1 Q9Y5S8 3/20 0.61
SMPD3 Q9NY59 3/20 0.59
MAPT P10636 5/20 0.56
MAPK14 Q16539 4/20 0.56
TP53 P04637 4/20 0.56
MAPK13 O15264 3/20 0.56
MAPK12 P53778 3/20 0.56
MAPK11 Q15759 3/20 0.56
RAF1 P04049 2/20 0.56
BRAF P15056 2/20 0.56
GCGR P47871 2/20 0.56
CSNK1D P48730 2/20 0.55
CSNK1E P49674 2/20 0.55
KDM4E B2RXH2 2/20 0.55
ALDH1A1 P00352 2/20 0.55
HPGD P15428 2/20 0.55
CIT O14578 1/20 0.55
GAK O14976 1/20 0.55
RIPK2 O43353 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12103632 0.91 SMPD3 (0.71) ALOX5NOX1SMPD3MAPTMAPK14
SCHEMBL6469493 0.88 ALOX5 (0.67) ALOX5NOX1SMPD3MAPTMAPK14
SCHEMBL12152244 0.88 NOX1 (0.68) ALOX5NOX1SMPD3MAPTMAPK14
SCHEMBL11595659 0.86 SMPD3 (0.76) ALOX5NOX1SMPD3MAPTMAPK14
SCHEMBL12103631 0.86 NOX1 (0.64) ALOX5NOX1SMPD3MAPTMAPK14
SCHEMBL12152166 0.85 ALOX5 (0.66) ALOX5NOX1SMPD3MAPTMAPK14
SCHEMBL12311036 0.85 KDM4E (0.67) ALOX5NOX1SMPD3MAPTMAPK14
SCHEMBL8010209 0.84 NOX1 (0.76) ALOX5NOX1SMPD3MAPTMAPK14
SCHEMBL4553131 0.83 ALOX5 (1.00) ALOX5MAPTMAPK14MAPK13MAPK12
SCHEMBL6468989 0.83 ALOX5 (0.78) ALOX5MAPTMAPK14MAPK13MAPK12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8999430-B2 Method of manufacturing display element KONICA MINOLTA HOLDINGS, INC. (JP) 2015-04-07 US disclosed
US-8384982-B2 Display element KONICA MINOLTA HOLDINGS, INC. (JP) 2013-02-26 US disclosed
US-8049948-B2 Process for producing electrochemical display element and electrochemical display element KONICA MINOLTA HOLDINGS, INC. (JP) 2011-11-01 US disclosed
US-8014056-B2 Display element and method of driving the same KONICA MINOLTA HOLDINGS, INC. (JP) 2011-09-06 US disclosed
US-8004742-B2 Electrochromic display device KONICA MINOLTA HOLDINGS, INC. (JP) 2011-08-23 US disclosed
US-20110058244-A1 ELECTROCHROMIC DISPLAY ELEMENT KONICA MINOLTA HOLDINGS, INC. (JP) 2011-03-10 US disclosed
US-20100213813-A1 DISPLAY ELEMENT EDISON INNOVATIONS LLC 2010-08-26 US disclosed
US-20100166946-A1 METHOD OF MANUFACTURING DISPLAY ELEMENT KONICA MINOLTA HOLDINGS, INC. (JP) 2010-07-01 US disclosed
US-20100134864-A1 PROCESS FOR PRODUCING ELECTROCHEMICAL DISPLAY ELEMENT AND ELECTROCHEMICAL DISPLAY ELEMENT KONICA MINOLTA HOLDINGS ,INC. (JP) 2010-06-03 US disclosed
US-20100091353-A1 DISPLAY ELEMENT AND METHOD OF DRIVING THE SAME KONICA MINOLTA HOLDINGS, INC. (JP) 2010-04-15 US disclosed
EP-2149816-A1 METHOD FOR PRODUCTION OF DISPLAY ELEMENT Konica Minolta Holdings, Inc. (JP) 2010-02-03 EP disclosed
US-20090316249-A1 ELECTROCHROMIC DISPLAY DEVICE KONICA MINOLTA HOLDINGS, INC. (JP) 2009-12-24 US disclosed
US-7619803-B2 Electrochromic display element and full-color electrochromic display element KONICA MINOLTA HOLDINGS, INC. (JP) 2009-11-17 US disclosed
US-20090027757-A1 ELECTROCHROMIC DISPLAY ELEMENT AND FULL-COLOR ELECTROCHROMIC DISPLAY ELEMENT KONICA MINOLTA HOLDINGS, INC. (JP) 2009-01-29 US disclosed