Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 4/20 | 0.41 |
| ▸ | FAAH | O00519 | 3/20 | 0.41 |
| ▸ | KCNN4 | O15554 | 3/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.39 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11598693 | 0.81 | HDAC1 (0.42) | L3MBTL1LMNAMAPTTDP1CES1 | |
| SCHEMBL34229 | 0.80 | HDAC1 (0.51) | L3MBTL1LMNAMAPTTDP1CES1 | |
| SCHEMBL13865461 | 0.78 | KCNN4 (0.47) | MAPTCES1KCNN4PTPN1GSK3B | |
| SCHEMBL1308478 | 0.72 | TDP1 (0.79) | L3MBTL1LMNAMAPTTDP1CES1 | |
| SCHEMBL8939158 | 0.71 | KCNN4 (0.48) | MAPTCES1KCNN4GSK3BNPSR1 | |
| SCHEMBL7384285 | 0.71 | TDP1 (0.83) | L3MBTL1LMNAMAPTTDP1CES1 | |
| SCHEMBL7393801 | 0.71 | TDP1 (0.83) | L3MBTL1LMNAMAPTTDP1CES1 | |
| SCHEMBL28609280 | 0.71 | TDP1 (0.83) | L3MBTL1LMNAMAPTTDP1CES1 | |
| SCHEMBL559268 | 0.71 | TDP1 (0.83) | L3MBTL1LMNAMAPTTDP1CES1 | |
| SCHEMBL8939163 | 0.70 | KCNN4 (0.44) | L3MBTL1LMNAKCNN4CYP2C19HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4075407-A | HETEROCYCLIC PHOSPHONIUM SALTS | G. D. SEARLE & CO. (US) | 1978-02-21 | — | — | US | disclosed |
| US-4056562-A | 3,5-Bisoxygenated 2-(ω-halo-3-oxygenated-1-alkenyl)-cyclopentane-1-heptanoic acids and derivatives thereof | G. D. SEARLE & CO. (US) | 1977-11-01 | — | — | US | disclosed |
| US-4041050-A | 3,5-Bisoxygenated 2-(ω-halo-3-oxo-1-alkenyl)-cyclopentane-1-heptanoic acids and derivatives thereof | G. D. SEARLE & CO. (US) | 1977-08-09 | — | — | US | disclosed |
| US-3997588-A | 3,5-Bisoxygenated 2-(ω-halo-3-oxygenated-1-alkenyl)-cyclopentane-1-heptanoic acids and derivatives thereof | G. D. SEARLE & CO. (US) | 1976-12-14 | — | — | US | disclosed |