Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.83 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.83 |
| ▸ | MAPT | P10636 | 2/20 | 0.83 |
| ▸ | LMNA | P02545 | 1/20 | 0.83 |
| ▸ | HDAC1 | Q13547 | 8/20 | 0.74 |
| ▸ | HDAC8 | Q9BY41 | 7/20 | 0.74 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.74 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.74 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.74 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.74 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.74 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.74 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.74 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.74 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.74 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | CASP3 | P42574 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.60 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28609280 | 1.00 | TDP1 (0.83) | TDP1L3MBTL1MAPTLMNAHDAC1 | |
| SCHEMBL7393801 | 1.00 | TDP1 (0.83) | TDP1L3MBTL1MAPTLMNAHDAC1 | |
| SCHEMBL7384285 | 1.00 | TDP1 (0.83) | TDP1L3MBTL1MAPTLMNAHDAC1 | |
| SCHEMBL1308478 | 0.98 | TDP1 (0.79) | TDP1L3MBTL1MAPTLMNAHDAC1 | |
| SCHEMBL2116192 | 0.94 | TDP1 (0.72) | TDP1L3MBTL1MAPTLMNAHDAC1 | |
| SCHEMBL9057671 | 0.91 | TDP1 (1.00) | TDP1L3MBTL1MAPTLMNAHDAC1 | |
| SCHEMBL27516050 | 0.91 | TDP1 (1.00) | TDP1L3MBTL1MAPTLMNAHDAC1 | |
| SCHEMBL8519287 | 0.91 | TDP1 (1.00) | TDP1L3MBTL1MAPTLMNAHDAC1 | |
| SCHEMBL7068671 | 0.89 | TDP1 (0.95) | TDP1L3MBTL1MAPTLMNAHDAC1 | |
| SCHEMBL9352420 | 0.85 | HDAC1 (1.00) | TDP1L3MBTL1MAPTLMNAHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9110069-B2 | Luminescent compounds | SETA BIOMEDICALS, LLC (US) | 2015-08-18 | — | — | US | disclosed |
| EP-2129788-B1 | LUMINESCENT COMPOUNDS | SETA BIOMEDICALS LLC (US) | 2014-09-03 | — | — | EP | disclosed |
| US-20140086844-A1 | LUMINESCENT COMPOUNDS | SETA BIOMEDICALS, LLC (US) | 2014-03-27 | — | — | US | disclosed |
| US-8642014-B2 | Luminescent compounds | SETA BIOMEDICALS, LLC (US) | 2014-02-04 | — | — | US | disclosed |
| US-8552027-B2 | Luminescent compounds | SETA BIOMEDICALS, LLC (US) | 2013-10-08 | — | — | US | disclosed |
| US-20120035346-A1 | LUMINESCENT COMPOUNDS | SETA BIOMEDICALS, LLC | 2012-02-09 | — | — | US | disclosed |
| US-20100266507-A1 | LUMINESCENT COMPOUNDS | SETA BIOMEDICALS, LLC | 2010-10-21 | — | — | US | disclosed |
| WO-2010083471-A1 | LUMINESCENT COMPOUNDS | SETA BIOMEDICALS, LLC (US) | 2010-07-22 | — | — | WO | disclosed |
| EP-2129788-A2 | LUMINESCENT COMPOUNDS | Seta Biomedicals, LLC (US) | 2009-12-09 | — | — | EP | disclosed |
| US-7411068-B2 | Luminescent compounds | SETA BIOMEDICALS, LLC | 2008-08-12 | — | — | US | disclosed |
| WO-2008094637-A2 | LUMINESCENT COMPOUNDS | SETA BIOMEDICALS. LLC (US) | 2008-08-07 | — | — | WO | disclosed |
| US-20070281363-A1 | Reporter molecules based on squaric, croconic, and/or rhodizonic acid; photoluminescence | Terpetschnig, Ewald (US) | 2007-12-06 | — | — | US | disclosed |
| US-7250517-B2 | Luminescent compounds | Terpetschnig, Ewald A. (US) | 2007-07-31 | — | — | US | disclosed |
| US-20050202565-A1 | Luminescent compounds | SETA BIOMEDICALS, LLC | 2005-09-15 | — | — | US | disclosed |
| US-20040166515-A1 | Luminescent compounds | TERPETSCHNIG, EWALD A. | 2004-08-26 | — | — | US | disclosed |
| US-5864039-A | THERAPEUTIC TREATMENT OF VARIOUS GASTROINTESTINAL DISEASES, CENTRAL NERVOUS DISORDERS, CARDIOVASCULAR DISORDERS, URINARY DISEASES, UROGENITAL DISORDERS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1999-01-26 | — | — | US | disclosed |
| EP-0873990-A1 | BENZOIC ACID COMPOUNDS AND MEDICINAL USE THEREOF | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1998-10-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100266507-A1 | LUMINESCENT COMPOUNDS | SQLE, COASY, ZKSCAN2 | TDP1 4554/4885L3MBTL1 398/4885MAPT 4099/4885 |
| US-20140086844-A1 | LUMINESCENT COMPOUNDS | PHOSPHO1, PGLS, PFAS | TDP1 1854/4885L3MBTL1 862/4885MAPT 1439/4885 |
| US-20120035346-A1 | LUMINESCENT COMPOUNDS | PHOSPHO1, PGLS, PFAS | TDP1 2133/4885L3MBTL1 791/4885MAPT 1265/4885 |
| US-20040166515-A1 | Luminescent compounds | RORC, NR2E3, RORB | TDP1 4285/4885L3MBTL1 929/4885MAPT 4542/4885 |
| US-20070281363-A1 | Reporter molecules based on squaric, croconic, and/or rhodizonic acid; photoluminescence | SPR, SRRT, SQLE | TDP1 4192/4885L3MBTL1 2272/4885MAPT 3790/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.