Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 13/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 12/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 12/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 12/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 12/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 11/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 11/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 10/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 10/20 | 0.51 |
| ▸ | HDAC9 | Q9UKV0 | 10/20 | 0.51 |
| ▸ | HDAC5 | Q9UQL6 | 10/20 | 0.51 |
| ▸ | FAAH | O00519 | 3/20 | 0.44 |
| ▸ | CES1 | P23141 | 3/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | NCOR1 | O75376 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11595736 | 0.80 | L3MBTL1 (0.42) | HDAC1HDAC2HDAC3HDAC10HDAC11 | |
| SCHEMBL11598693 | 0.80 | HDAC1 (0.42) | HDAC1HDAC2HDAC3HDAC10HDAC11 | |
| SCHEMBL8939158 | 0.70 | KCNN4 (0.48) | CES1MAPT | |
| SCHEMBL8939183 | 0.69 | ALDH1A1 (0.49) | — | |
| Chlorobenzene SCHEMBL28101923 | 0.69 | FOLH1 (0.59) | HDAC1HDAC2HDAC3HDAC10HDAC11 | |
| SCHEMBL8939163 | 0.69 | KCNN4 (0.44) | L3MBTL1LMNA | |
| SCHEMBL13868873 | 0.69 | KCNN4 (0.47) | HDAC1HDAC2HDAC3HDAC10HDAC11 | |
| SCHEMBL29679704 | 0.69 | KCNN4 (0.47) | MAPT | |
| SCHEMBL13865461 | 0.69 | KCNN4 (0.47) | HDAC1HDAC2HDAC3HDAC10HDAC11 | |
| SCHEMBL13828216 | 0.69 | OPRM1 (0.55) | HDAC1HDAC2HDAC3HDAC10HDAC11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250127797-A1 | PRODRUG COMPRISING A DRUG-LINKER CONJUGATE | ASCENDIS PHARMA A/S (DK) | 2025-04-24 | — | — | US | disclosed |
| US-20240041897-A1 | PRODRUG COMPRISING A DRUG LINKER CONJUGATE | ASCENDIS PHARMA GMBH (DE) | 2024-02-08 | — | — | US | disclosed |
| US-20220331334-A1 | Prodrug Comprising a Drug-Linker Conjugate | ASCENDIS PHARMA A/S (DK) | 2022-10-20 | — | — | US | disclosed |
| EP-3981761-A2 | INTERMEDIATES FOR PRODRUGS | Ascendis Pharma A/S (DK) | 2022-04-13 | — | — | EP | disclosed |
| EP-2596805-B1 | Prodrug comprising a drug-linker conjugate | ASCENDIS PHARMA AS (DK) | 2021-10-27 | — | — | EP | disclosed |
| US-20200046725-A1 | Prodrug Comprising a Drug Linker Conjugate | ASCENDIS PHARMA A/S (DK) | 2020-02-13 | — | — | US | disclosed |
| EP-2237799-B1 | PRODRUG COMPRISING A SELF-CLEAVABLE LINKER | ASCENDIS PHARMA AS (DK) | 2019-04-10 | — | — | EP | disclosed |
| US-20170100490-A1 | Prodrug Comprising a Drug Linker Conjugate | ASCENDIS PHARMA A/S (DK) | 2017-04-13 | — | — | US | disclosed |
| US-20150057221-A1 | PRODRUG COMPRISING A DRUG LINKER CONJUGATE | ASCENDIS PHARMA AS (DK) | 2015-02-26 | — | — | US | disclosed |
| US-8906847-B2 | Prodrug comprising a drug linker conjugate | ASCENDIS PHARMA A/S (DK) | 2014-12-09 | — | — | US | disclosed |
| EP-2596805-A1 | Prodrug comprising a drug linker conjugate | Ascendis Pharma A/S (DK) | 2013-05-29 | — | — | EP | disclosed |
| US-20110053848-A1 | PRODRUG COMPRISING A DRUG LINKER CONJUGATE | ASCENDIS PHARMA AS (DK) | 2011-03-03 | — | — | US | disclosed |
| EP-2237799-A2 | PRODRUG COMPRISING A SELF-CLEAVABLE LINKER | Ascendis Pharma AS (DK) | 2010-10-13 | — | — | EP | disclosed |
| WO-2009095479-A2 | PRODRUG COMPRISING A SELF-CLEAVABLE LINKER | ASCENDIS PHARMA AS (DK) | 2009-08-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150057221-A1 | PRODRUG COMPRISING A DRUG LINKER CONJUGATE | H1-0, H1-3, H1-2 | HDAC1 437/4885HDAC2 795/4885HDAC3 445/4885 |
| US-20170100490-A1 | Prodrug Comprising a Drug Linker Conjugate | H1-0, H1-3, H1-2 | HDAC1 437/4885HDAC2 795/4885HDAC3 445/4885 |
| US-20110053848-A1 | PRODRUG COMPRISING A DRUG LINKER CONJUGATE | H1-0, H1-3, H1-2 | HDAC1 439/4885HDAC2 794/4885HDAC3 444/4885 |
| US-20200046725-A1 | Prodrug Comprising a Drug Linker Conjugate | H1-0, H1-3, H1-2 | HDAC1 439/4885HDAC2 792/4885HDAC3 446/4885 |
| US-20240041897-A1 | PRODRUG COMPRISING A DRUG LINKER CONJUGATE | H1-0, H1-3, H1-2 | HDAC1 437/4885HDAC2 795/4885HDAC3 445/4885 |
| US-20220331334-A1 | Prodrug Comprising a Drug-Linker Conjugate | H1-0, H1-3, DLST | HDAC1 561/4885HDAC2 893/4885HDAC3 579/4885 |
| US-20250127797-A1 | PRODRUG COMPRISING A DRUG-LINKER CONJUGATE | H1-0, H1-3, DLST | HDAC1 561/4885HDAC2 893/4885HDAC3 579/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.