Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | AKT1 | P31749 | 1/20 | 0.44 |
| ▸ | CNKSR1 | Q969H4 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11169141 | 0.90 | ALDH1A1 (0.62) | ALDH1A1RECQLCYP2C9PPARGSMN1; SMN2 | |
| SCHEMBL11169969 | 0.87 | ALDH1A1 (0.59) | ALDH1A1RECQLCYP2C9PPARGSMN1; SMN2 | |
| SCHEMBL11166550 | 0.86 | ALDH1A1 (0.60) | ALDH1A1RECQLCYP2C9PPARGSMN1; SMN2 | |
| SCHEMBL11165367 | 0.82 | ALDH1A1 (0.58) | ALDH1A1RECQLCYP2C9PPARGSMN1; SMN2 | |
| SCHEMBL11169713 | 0.82 | ALDH1A1 (0.57) | ALDH1A1RECQLCYP2C9PPARGSMN1; SMN2 | |
| SCHEMBL11170337 | 0.81 | ALDH1A1 (0.74) | ALDH1A1RECQLCYP2C9SMN1; SMN2L3MBTL1 | |
| SCHEMBL11172544 | 0.80 | AKR1B1 (0.59) | CYP2C9PPARGPTGDR2TDP1KMT2A | |
| SCHEMBL11160209 | 0.77 | KMT2A (0.54) | ALDH1A1CYP2C9PPARGAKT1MAPT | |
| SCHEMBL10731198 | 0.75 | CYP1A2 (0.74) | ALDH1A1RECQLCYP2C9SMN1; SMN2L3MBTL1 | |
| SCHEMBL11160841 | 0.74 | AKR1B1 (0.58) | ALDH1A1CYP2C9PPARGGAAPTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0002895-A1 | Enzyme inhibitory phthalazin-4-ylacetic acid derivatives, pharmaceutical compositions thereof, and process for their manufacture | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1979-07-11 | — | — | EP | disclosed |