Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 4/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 4/20 | 0.47 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.47 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8077438 | 0.91 | FOLH1 (0.51) | ADRB2ADRB1KDM4EALDH1A1LMNA | |
| SCHEMBL4670569 | 0.89 | ADRB2 (0.48) | ADRB2ADRB1KDM4EALDH1A1LMNA | |
| SCHEMBL14080487 | 0.89 | ADRB2 (0.48) | ADRB2ADRB1KDM4EALDH1A1LMNA | |
| SCHEMBL14080472 | 0.89 | ADRB2 (0.48) | ADRB2ADRB1KDM4EALDH1A1LMNA | |
| SCHEMBL11596670 | 0.86 | ADRB2 (0.55) | ADRB2ADRB1ADRA1DADRA1AADRA1B | |
| Cadaverine Tartrate SCHEMBL14080565 | 0.85 | F2 (0.46) | ADRB2ADRB1KDM4EALDH1A1HPGD | |
| SCHEMBL11596475 | 0.83 | ADRB2 (0.50) | ADRB2ADRB1ADRA1DADRA1AADRA1B | |
| SCHEMBL6897408 | 0.82 | FOLH1 (0.49) | ADRB2ADRB1ADRA1DADRA1AADRA1B | |
| SCHEMBL6897412 | 0.82 | FOLH1 (0.49) | ADRB2ADRB1ADRA1DADRA1AADRA1B | |
| SCHEMBL12158808 | 0.81 | ADRB2 (0.58) | ADRB2ADRB1CYP2D6LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4101579-A | Phenethanolamine ethers | ALLEN & HANBURYS LIMITED (GB) | 1978-07-18 | — | — | US | disclosed |