SCHEMBL4670569

SCHEMBL4670569

COC(=O)c1cc(C(O)CNC(C)(C)C)ccc1OCc1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ADRB2 P07550 1/20 0.48
ADRB1 P08588 1/20 0.48
ADRB3 P13945 1/20 0.48
F2 P00734 1/20 0.48
F7 P08709 1/20 0.48
HPGD P15428 2/20 0.44
MEN1 O00255 1/20 0.44
KMT2A Q03164 1/20 0.44
KDM4E B2RXH2 1/20 0.44
ALDH1A1 P00352 1/20 0.44
CTSV O60911 1/20 0.43
CTSL P07711 1/20 0.43
LMNA P02545 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14080472 1.00 ADRB2 (0.48) ADRB2ADRB1ADRB3F2F7
SCHEMBL14080487 1.00 ADRB2 (0.48) ADRB2ADRB1ADRB3F2F7
Cadaverine Tartrate SCHEMBL14080565 0.96 F2 (0.46) ADRB2ADRB1ADRB3F2F7
SCHEMBL11748288 0.92 ADRB2 (0.49) ADRB2ADRB1ADRB3F2F7
SCHEMBL8077438 0.91 FOLH1 (0.51) ADRB2ADRB1ADRB3MEN1KMT2A
SCHEMBL11596019 0.89 ADRB2 (0.47) ADRB2ADRB1ADRB3F2F7
SCHEMBL965193 0.84 F2 (0.49) ADRB2ADRB1ADRB3F2F7
SCHEMBL965192 0.84 F2 (0.49) ADRB2ADRB1ADRB3F2F7
SCHEMBL7109940 0.82 F2 (0.47) ADRB2ADRB1ADRB3F2F7
Iodide SCHEMBL9574103 0.81 F2 (0.47) ADRB2ADRB1ADRB3F2F7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE43984-E1 Process for preparing isomers of salbutamol CIPLA LIMITED (IN) 2013-02-05 US claimed
US-RE43844-E1 Process for preparing isomers of salbutamol CIPLA LIMITED (IN) 2012-12-04 US claimed
US-6995286-B2 Resolution of racemic mixture using tartaric acid CIPLA LIMITED (IN) 2006-02-07 US claimed
EP-0763010-B1 ENANTIOSELECTIVE PREPARATION OF OPTICALLY PURE ALBUTEROL SEPRACOR INC (US) 2000-08-30 EP claimed
EP-0763010-A4 ENANTIOSELECTIVE PREPARATION OF OPTICALLY PURE ALBUTEROL SEPRACOR INC (US) 1997-07-16 EP claimed
EP-0763010-A1 ENANTIOSELECTIVE PREPARATION OF OPTICALLY PURE ALBUTEROL SEPRACOR, INC. (US) 1997-03-19 EP claimed
US-5545745-A DISSOLVING MIXTURE OF METHYL-5(2-(1,1-DIMETHYLETHYL)AMINO)-1-HYROXYETHYL)-2-(PHENYL -METHOXY)BENZOATE AND A CHIRAL ACID, SALT FORMATION, COOLING, NEUTRALIZING SALT WITH BASE, REDUCTION, DEBENZYLATION SEPRACOR, INC. (US) 1996-08-13 US claimed
WO-1995032178-A1 ENANTIOSELECTIVE PREPARATION OF OPTICALLY PURE ALBUTEROL SEPRACOR, INC. (US) 1995-11-30 WO claimed
US-20240391866-A1 PROCESS FOR THE PREPARATION OF THE SALBUTAMOL INTERMEDIATE YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2024-11-28 US disclosed
US-RE43984-E1 Process for preparing isomers of salbutamol CIPLA LIMITED (IN) 2013-02-05 US disclosed
US-RE43844-E1 Process for preparing isomers of salbutamol CIPLA LIMITED (IN) 2012-12-04 US disclosed
EP-1935872-A1 Process for obtaining the R-enantiomer of salbutamol Stirling Products Limited (AU) 2008-06-25 EP disclosed
WO-2008070909-A1 PROCESS FOR OBTAINING THE R-ENANTIOMER OF SALBUTAMOL STIRLING PRODUCTS LIMITED (AU) 2008-06-19 WO disclosed
WO-2007101872-A1 PROCESS FOR THE ENANTIOMERIC ENRICHMENT OF SALBUTAMOL AND SALBUTAMOL PRECURSORS STIRLING PRODUCTS LTD. (AU) 2007-09-13 WO disclosed
EP-0763010-A1 ENANTIOSELECTIVE PREPARATION OF OPTICALLY PURE ALBUTEROL SEPRACOR, INC. (US) 1997-03-19 EP disclosed
EP-0763010-A1 ENANTIOSELECTIVE PREPARATION OF OPTICALLY PURE ALBUTEROL SEPRACOR, INC. (US) 1997-03-19 EP disclosed
US-5545745-A DISSOLVING MIXTURE OF METHYL-5(2-(1,1-DIMETHYLETHYL)AMINO)-1-HYROXYETHYL)-2-(PHENYL -METHOXY)BENZOATE AND A CHIRAL ACID, SALT FORMATION, COOLING, NEUTRALIZING SALT WITH BASE, REDUCTION, DEBENZYLATION SEPRACOR, INC. (US) 1996-08-13 US disclosed
US-5545745-A DISSOLVING MIXTURE OF METHYL-5(2-(1,1-DIMETHYLETHYL)AMINO)-1-HYROXYETHYL)-2-(PHENYL -METHOXY)BENZOATE AND A CHIRAL ACID, SALT FORMATION, COOLING, NEUTRALIZING SALT WITH BASE, REDUCTION, DEBENZYLATION SEPRACOR, INC. (US) 1996-08-13 US disclosed
WO-1995032178-A1 ENANTIOSELECTIVE PREPARATION OF OPTICALLY PURE ALBUTEROL SEPRACOR, INC. (US) 1995-11-30 WO disclosed
WO-1995032178-A1 ENANTIOSELECTIVE PREPARATION OF OPTICALLY PURE ALBUTEROL SEPRACOR, INC. (US) 1995-11-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240391866-A1 PROCESS FOR THE PREPARATION OF THE SALBUTAMOL INTERMEDIATE ADRB3, ADH1C, ADRB2 ADRB2 3/4885ADRB1 4/4885ADRB3 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.