Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.51 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.47 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CTSV | O60911 | 2/20 | 0.47 |
| ▸ | CTSL | P07711 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14080487 | 0.91 | ADRB2 (0.48) | ADRB1ADRB3ADRB2KDM4EALDH1A1 | |
| SCHEMBL4670569 | 0.91 | ADRB2 (0.48) | ADRB1ADRB3ADRB2KDM4EALDH1A1 | |
| SCHEMBL11596019 | 0.91 | ADRB2 (0.47) | ADRB1ADRB3ADRB2KDM4EALDH1A1 | |
| SCHEMBL14080472 | 0.91 | ADRB2 (0.48) | ADRB1ADRB3ADRB2KDM4EALDH1A1 | |
| Cadaverine Tartrate SCHEMBL14080565 | 0.87 | F2 (0.46) | ADRB1ADRB3ADRB2KDM4EALDH1A1 | |
| SCHEMBL11597255 | 0.85 | FOLH1 (0.52) | FOLH1ADRB1ADRB3ADRB2KDM4E | |
| SCHEMBL11596349 | 0.83 | ADRB2 (0.48) | ADRB1ADRB2ALDH1A1KMT2ALMNA | |
| SCHEMBL12158787 | 0.83 | ADRB2 (0.58) | ADRB1ADRB2LMNATSHRHIF1A | |
| SCHEMBL12158808 | 0.83 | ADRB2 (0.58) | ADRB1ADRB2LMNATSHRHIF1A | |
| SCHEMBL4667082 | 0.83 | ADRB2 (0.58) | ADRB1ADRB2LMNATSHRHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0763010-B1 | ENANTIOSELECTIVE PREPARATION OF OPTICALLY PURE ALBUTEROL | SEPRACOR INC (US) | 2000-08-30 | — | — | EP | claimed |
| EP-0763010-B1 | ENANTIOSELECTIVE PREPARATION OF OPTICALLY PURE ALBUTEROL | SEPRACOR INC (US) | 2000-08-30 | — | — | EP | disclosed |
| EP-0763010-A4 | ENANTIOSELECTIVE PREPARATION OF OPTICALLY PURE ALBUTEROL | SEPRACOR INC (US) | 1997-07-16 | — | — | EP | disclosed |
| EP-0763010-A1 | ENANTIOSELECTIVE PREPARATION OF OPTICALLY PURE ALBUTEROL | SEPRACOR, INC. (US) | 1997-03-19 | — | — | EP | disclosed |
| US-5545745-A | DISSOLVING MIXTURE OF METHYL-5(2-(1,1-DIMETHYLETHYL)AMINO)-1-HYROXYETHYL)-2-(PHENYL -METHOXY)BENZOATE AND A CHIRAL ACID, SALT FORMATION, COOLING, NEUTRALIZING SALT WITH BASE, REDUCTION, DEBENZYLATION | SEPRACOR, INC. (US) | 1996-08-13 | — | — | US | disclosed |
| WO-1995032178-A1 | ENANTIOSELECTIVE PREPARATION OF OPTICALLY PURE ALBUTEROL | SEPRACOR, INC. (US) | 1995-11-30 | — | — | WO | disclosed |