Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 17/20 | 0.40 |
| ▸ | RAB9A | P51151 | 17/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13886960 | 0.99 | RAB9A (0.39) | NPC1RAB9APOLBATMHPGD | |
| SCHEMBL1163039 | 0.86 | MAPT (0.44) | POLBHPGDALDH1A1TP53TSHR | |
| SCHEMBL13887124 | 0.85 | MAPT (0.44) | HPGDALDH1A1TP53TSHRMAPT | |
| SCHEMBL13886962 | 0.84 | RHOC (0.41) | NPC1RAB9AHPGDTP53MAPT | |
| SCHEMBL13886881 | 0.83 | HPGD (0.34) | NPC1RAB9APOLBHPGDTSHR | |
| SCHEMBL1097217 | 0.80 | HPGD (0.45) | NPC1RAB9AHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL1096827 | 0.79 | HPGD (0.46) | NPC1RAB9APOLBHPGDSMN1; SMN2 | |
| SCHEMBL13887120 | 0.79 | RAB9A (0.39) | NPC1RAB9AHPGDSMN1; SMN2ALDH1A1 | |
| SCHEMBL13886797 | 0.78 | EPHX2 (0.38) | NPC1RAB9ASMN1; SMN2ALDH1A1TP53 | |
| SCHEMBL13887127 | 0.78 | F10 (0.33) | SMN1; SMN2ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8153670-B2 | Factor Xa inhibitors | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2012-04-10 | — | — | US | disclosed |
| US-20090298806-A1 | FACTOR XA INHIBITORS | MILLENNIUM PHARMACEUTICALS, INC. | 2009-12-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090298806-A1 | FACTOR XA INHIBITORS | TFPI, F12, F11 | NPC1 887/4885RAB9A 2543/4885POLB 3172/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.