Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 11/20 | 0.43 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 2/20 | 0.36 |
| ▸ | MAOB | P27338 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL11597653 | 0.85 | MAPT (0.44) | KDM4EMAPTAPOBEC3AALDH1A1GAA | |
| Iodide SCHEMBL11599406 | 0.79 | MAPT (0.62) | KDM4EMAPTAPOBEC3AALDH1A1GAA | |
| SCHEMBL12201136 | 0.73 | KDM4E (0.79) | KDM4EMAPTAPOBEC3AALDH1A1GAA | |
| SCHEMBL13646750 | 0.69 | MAPT (0.66) | KDM4EMAPTAPOBEC3AALDH1A1GAA | |
| SCHEMBL14403381 | 0.68 | MAPT (0.75) | KDM4EMAPTAPOBEC3AALDH1A1GAA | |
| Bromide SCHEMBL6120521 | 0.68 | MAPT (0.64) | KDM4EMAPTAPOBEC3AALDH1A1GAA | |
| SCHEMBL6121100 | 0.68 | MAPT (0.57) | KDM4EMAPTAPOBEC3AALDH1A1GAA | |
| SCHEMBL12201134 | 0.68 | MAPT (0.73) | KDM4EMAPTAPOBEC3AALDH1A1CYP2D6 | |
| Iodide SCHEMBL2987038 | 0.67 | MAPT (0.78) | KDM4EMAPTAPOBEC3AALDH1A1GAA | |
| SCHEMBL1049070 | 0.67 | CYP2D6 (0.64) | KDM4EMAPTAPOBEC3AALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4115122-A | Internal latent image silver halide emulsion containing a heterocyclic quaternary salt having a propargyl or a butyryl containing substituent | FUJI PHOTO FILM CO., LTD. (JP) | 1978-09-19 | — | — | US | claimed |
| US-4115122-A | Internal latent image silver halide emulsion containing a heterocyclic quaternary salt having a propargyl or a butyryl containing substituent | FUJI PHOTO FILM CO., LTD. (JP) | 1978-09-19 | — | — | US | disclosed |