Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.65 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 7/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.44 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.43 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.43 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.43 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.43 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.42 |
| ▸ | TIMP3 | P35625 | 1/20 | 0.42 |
| ▸ | NT5E | P21589 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11429045 | 0.93 | POLB (0.57) | APEX1MAPTMEN1KMT2APOLB | |
| SCHEMBL11429040 | 0.92 | POLB (0.56) | APEX1MAPTMEN1KMT2APOLB | |
| SCHEMBL8755454 | 0.89 | APEX1 (0.70) | APEX1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL10412672 | 0.89 | APEX1 (0.69) | APEX1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL11424495 | 0.88 | APEX1 (0.49) | APEX1RAB9AMAPTMEN1KMT2A | |
| Lindane SCHEMBL11436245 | 0.83 | APEX1 (0.45) | APEX1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL11597795 | 0.81 | APEX1 (0.69) | APEX1MAPTMEN1KMT2APOLB | |
| SCHEMBL11433857 | 0.81 | APEX1 (0.58) | APEX1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL11433142 | 0.81 | APEX1 (0.56) | APEX1RAB9AMAPTMEN1KMT2A | |
| SCHEMBL11436623 | 0.81 | APEX1 (0.58) | APEX1RAB9AMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4129591-A | INHIBITORS OF THE COMPLEMENT SYSTEM | AMERICAN CYANAMID COMPANY (US) | 1978-12-12 | — | — | US | disclosed |