Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | BLM | P54132 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 7/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | GMNN | O75496 | 1/20 | 0.39 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11602422 | 0.85 | GAA (0.45) | ALDH1A1MEN1KMT2AHIF1ACYP3A4 | |
| SCHEMBL11598805 | 0.85 | CYP2C19 (0.39) | ALDH1A1MEN1KMT2AHIF1ACYP3A4 | |
| SCHEMBL1724042 | 0.81 | THRB (0.49) | ALDH1A1KMT2AHIF1ACYP3A4TSHR | |
| SCHEMBL2265057 | 0.76 | GAA (0.55) | ALDH1A1MEN1KMT2AHIF1ACYP3A4 | |
| SCHEMBL11264836 | 0.76 | ALDH1A1 (0.58) | ALDH1A1MEN1KMT2AHIF1ACYP3A4 | |
| SCHEMBL5412953 | 0.73 | GAA (0.56) | ALDH1A1MEN1KMT2AHIF1ACYP3A4 | |
| SCHEMBL21569610 | 0.71 | GAA (0.48) | ALDH1A1MEN1KMT2AHIF1ACYP3A4 | |
| SCHEMBL18051656 | 0.71 | THRB (0.47) | ALDH1A1MEN1KMT2AHIF1ACYP3A4 | |
| SCHEMBL10651744 | 0.71 | GAA (0.60) | ALDH1A1MEN1KMT2AHIF1ACYP3A4 | |
| SCHEMBL11268882 | 0.71 | ALDH1A1 (0.60) | ALDH1A1MEN1KMT2AHIF1ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4091225-A | ALKYLATION, REDUCTION, TRANSESTERIFICATION | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1978-05-23 | — | — | US | disclosed |