Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 3/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 6/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18051656 | 0.85 | THRB (0.47) | THRBHIF1ACYP2C19ALDH1A1CYP3A4 | |
| SCHEMBL19846629 | 0.83 | THRB (0.51) | THRBHIF1ACYP2C19ALDH1A1CYP3A4 | |
| SCHEMBL28771131 | 0.83 | THRB (0.45) | THRBHIF1ACYP2C19ALDH1A1CYP3A4 | |
| SCHEMBL8034194 | 0.82 | HIF1A (0.59) | HIF1ACYP2C19ALDH1A1MAPK1MAPT | |
| SCHEMBL22195193 | 0.82 | THRB (0.47) | THRBHIF1ACYP2C19ALDH1A1CYP3A4 | |
| SCHEMBL11598808 | 0.81 | ALDH1A1 (0.43) | THRBHIF1ACYP2C19ALDH1A1CYP3A4 | |
| SCHEMBL3169549 | 0.79 | CYP2C19 (0.46) | THRBHIF1ACYP2C19ALDH1A1CYP3A4 | |
| SCHEMBL13704977 | 0.78 | THRB (0.44) | THRBHIF1ACYP2C19ALDH1A1CYP3A4 | |
| SCHEMBL12032239 | 0.78 | THRB (0.44) | THRBHIF1ACYP2C19ALDH1A1CYP3A4 | |
| SCHEMBL11598805 | 0.78 | CYP2C19 (0.39) | THRBHIF1ACYP2C19ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2403911-A1 | RADIATION CURABLE COATING COMPOUNDS COMPRISING DIACRYLATE | BASF SE (DE) | 2012-01-11 | — | — | EP | disclosed |
| WO-2010100051-A1 | RADIATION CURABLE COATING COMPOUNDS COMPRISING DIACRYLATE | BASF SE (DE) | 2010-09-10 | — | — | WO | disclosed |