Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1720646 | 0.92 | — | — | |
| SCHEMBL10774145 | 0.77 | ACP3 (0.48) | MAPK1CYP2D6ALDH1A1 | |
| SCHEMBL9860787 | 0.72 | HRH1 (0.39) | LMNAKDM4EL3MBTL1CYP2D6 | |
| SCHEMBL14490198 | 0.70 | LMNA (0.44) | LMNAMAPK1TSHRKDM4EL3MBTL1 | |
| SCHEMBL6299435 | 0.70 | ADRA2C (0.52) | LMNATSHRKDM4EADRA2AADRA2C | |
| SCHEMBL6895608 | 0.70 | LMNA (0.44) | LMNAMAPK1TSHRKDM4EL3MBTL1 | |
| SCHEMBL1100967 | 0.70 | LMNA (0.54) | LMNAKDM4EL3MBTL1HIF1ACYP2D6 | |
| SCHEMBL21504597 | 0.68 | ADRA2C (0.52) | LMNATSHRKDM4EADRA2AADRA2C | |
| Isopropylbenzene SCHEMBL10797529 | 0.68 | LMNA (0.50) | LMNAMAPK1TSHRKDM4EADRA2A | |
| SCHEMBL108052 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE29523-E | Olefinic polymers stabilized with thioacyl trivalent phosphorus compounds | BORG-WARNER CORPORATION (US) | 1978-01-24 | — | — | US | disclosed |