Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | RGS12 | O14924 | 1/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | THPO | P40225 | 1/20 | 0.43 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10252554 | 0.76 | ESR1 (0.46) | LMNATSHRCYP2D6CHRM2ADRA1A | |
| SCHEMBL6441510 | 0.74 | SRC (0.42) | LMNAMAPK1TSHRCYP2D6SRC | |
| SCHEMBL9330599 | 0.74 | LMNA (0.41) | LMNAMAPK1TSHRADRA2CCYP2D6 | |
| SCHEMBL2797910 | 0.72 | IDO1 (0.42) | MAPK1CYP2D6CYP3A4 | |
| SCHEMBL11524355 | 0.70 | DPP4 (0.50) | LMNAADRA2CCYP2D6HTR2AKDM4E | |
| SCHEMBL11599372 | 0.70 | LMNA (0.42) | LMNAMAPK1TSHRADRA2CCYP2D6 | |
| SCHEMBL14957448 | 0.70 | ADRA2C (0.44) | LMNATSHRADRA2CCYP2D6CHRM2 | |
| SCHEMBL2889714 | 0.69 | LMNA (0.62) | LMNAMAPK1TSHRADRA2CCYP2D6 | |
| Diphenylmethanol SCHEMBL10868602 | 0.69 | SMN1; SMN2 (0.61) | LMNAMAPK1TSHRADRA2CCYP2D6 | |
| Diphenylmethanol SCHEMBL41571 | 0.69 | SMN1; SMN2 (0.61) | LMNAMAPK1TSHRADRA2CCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1268581-B1 | STABLE INITIATOR SYSTEM | JOHNSON & JOHNSON VISION CARE (US) | 2004-11-24 | — | — | EP | disclosed |
| EP-1268581-A2 | STABLE INITIATOR SYSTEM | Johnson & Johnson Vision Care, Inc. (US) | 2003-01-02 | — | — | EP | disclosed |
| US-6414049-B1 | SILICONE, ACYLPHOSPHINE PROMOTER, ACID MIXTURE | JOHNSON & JOHNSON VISION CARE, INC. | 2002-07-02 | — | — | US | disclosed |
| WO-2001070824-A2 | STABLE INITIATOR SYSTEM | JOHNSON & JOHNSON VISION CARE, INC. (US) | 2001-09-27 | — | — | WO | disclosed |
| US-5075488-A | Fungicides | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1991-12-24 | — | — | US | disclosed |
| EP-0128006-B1 | A SOIL-DISEASE-CONTROLLING AGENT | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1991-09-18 | — | — | EP | disclosed |
| US-4709052-A | FUNGICIDES | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1987-11-24 | — | — | US | disclosed |
| EP-0128006-A2 | A soil-disease-controlling agent | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1984-12-12 | — | — | EP | disclosed |