Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PTPRB | P23467 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.34 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.34 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ATG4B | Q9Y4P1 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10865297 | 0.73 | KMT2A (0.42) | ALDH1A1KDM4EHPGDPOLBHTT | |
| SCHEMBL11601028 | 0.73 | ALDH1A1 (0.40) | ALDH1A1KDM4EHTTCASP1CASP7 | |
| SCHEMBL11832606 | 0.73 | ALDH1A1 (0.41) | ALDH1A1KDM4EHPGDPOLBKMT2A | |
| SCHEMBL9481549 | 0.70 | KDM4E (0.41) | ALDH1A1KDM4EHPGDPOLBPTPRB | |
| SCHEMBL11318564 | 0.70 | KMT2A (0.45) | ALDH1A1HPGDPOLBHSD17B10CDK2 | |
| SCHEMBL10905704 | 0.68 | KMT2A (0.40) | ALDH1A1KDM4EHPGDPOLBHSD17B10 | |
| SCHEMBL24317500 | 0.67 | CDK2 (0.44) | ALDH1A1KDM4EHPGDPOLBHTT | |
| SCHEMBL7936537 | 0.67 | RAD52 (0.44) | ALDH1A1KDM4EHPGDPOLBHTT | |
| SCHEMBL29532490 | 0.66 | MAPT (0.43) | ALDH1A1KDM4EHPGDPOLBHTT | |
| SCHEMBL24317498 | 0.66 | MAPT (0.43) | ALDH1A1KDM4EHPGDPOLBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE29834-E | PREPARED FROM 4-SULFONYL-1,8-NAPHTHOLACTAMS | BAYER AKTIENGESELLSCHAFT (DE) | 1978-11-14 | — | — | US | disclosed |
| US-3959310-A | BENZINDOLE | BAYER AKTIENGESELLSCHAFT (DT) | 1976-05-25 | — | — | US | disclosed |