Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SOAT1 | P35610 | 10/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.36 |
| ▸ | FEN1 | P39748 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | PTPRB | P23467 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10894850 | 0.81 | THRB (0.39) | KDM4EALDH1A1HPGDSOAT1ALOX5AP | |
| SCHEMBL27611345 | 0.76 | ALPL (0.41) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL27593199 | 0.76 | ALPL (0.41) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL23245997 | 0.74 | TSHR (0.46) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL2508510 | 0.73 | NR1H2 (0.47) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL29699286 | 0.73 | NR1H2 (0.47) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL10725242 | 0.72 | NR1H2 (0.49) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL9402093 | 0.72 | NR1H2 (0.49) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL8684492 | 0.72 | NR1H2 (0.49) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL10730459 | 0.72 | NR1H2 (0.49) | KDM4EALDH1A1HPGDHSD17B10GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5238950-A | Antagonist of platelet activating factor | SCHERING CORPORATION (US) | 1993-08-24 | — | — | US | disclosed |