Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.53 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.51 |
| ▸ | ESR1 | P03372 | 8/20 | 0.51 |
| ▸ | HSD17B1 | P14061 | 5/20 | 0.47 |
| ▸ | HSD17B2 | P37059 | 4/20 | 0.47 |
| ▸ | CLK1 | P49759 | 1/20 | 0.44 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8338171 | 0.91 | ESR1 (0.63) | MAOBMAOADYRK1AESR1HSD17B1 | |
| SCHEMBL11602025 | 0.85 | MAOB (0.70) | MAOBMAOAESR1 | |
| SCHEMBL8338493 | 0.85 | ESR1 (0.60) | MAOBMAOAESR1 | |
| SCHEMBL11599689 | 0.83 | ESR1 (0.71) | DYRK1AESR1CLK1DYRK1B | |
| SCHEMBL11598721 | 0.83 | ESR1 (0.56) | MAOBMAOADYRK1AESR1CLK1 | |
| SCHEMBL7506018 | 0.83 | ESR1 (0.59) | MAOBMAOAESR1 | |
| SCHEMBL11600909 | 0.81 | ESR1 (0.58) | MAOBESR1 | |
| SCHEMBL8341396 | 0.80 | ESR1 (0.76) | DYRK1AESR1HSD17B1HSD17B2CLK1 | |
| SCHEMBL9145308 | 0.80 | ESR1 (0.61) | MAOBDYRK1AESR1HSD17B1HSD17B2 | |
| SCHEMBL11600019 | 0.79 | LMNA (0.47) | MAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4075227-A | NONSTEROIDAL | ELI LILLY AND COMPANY (US) | 1978-02-21 | — | — | US | disclosed |