SCHEMBL11599808

SCHEMBL11599808

O=C(CS)Oc1ccccc1Br

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRM4 Q14833 3/20 0.42
RAB9A P51151 4/20 0.40
NPC1 O15118 3/20 0.40
ALDH1A1 P00352 4/20 0.39
KMT2A Q03164 6/20 0.39
MEN1 O00255 4/20 0.39
LMNA P02545 4/20 0.39
KDM4E B2RXH2 3/20 0.39
HPGD P15428 3/20 0.39
SMN1; SMN2 Q16637 3/20 0.39
MAPK1 P28482 1/20 0.39
HTT P42858 1/20 0.39
MAPT P10636 3/20 0.37
GAA P10253 1/20 0.37
STAT3 P40763 1/20 0.37
STAT1 P42224 1/20 0.37
HTR7 P34969 1/20 0.37
USP2 O75604 2/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
POLB P06746 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31621484 0.81 ELANE (0.46) GRM4RAB9ANPC1ALDH1A1KMT2A
SCHEMBL9034169 0.81 KMT2A (0.50) GRM4RAB9ANPC1ALDH1A1KMT2A
SCHEMBL27985912 0.81 GRM4 (0.42) GRM4RAB9ANPC1ALDH1A1KMT2A
SCHEMBL1343624 0.81 ELANE (0.46) GRM4RAB9ANPC1ALDH1A1KMT2A
SCHEMBL16416522 0.78 GRM4 (0.41) GRM4RAB9ANPC1ALDH1A1KMT2A
SCHEMBL17673232 0.78 ALOX15 (0.47) GRM4RAB9ANPC1ALDH1A1KMT2A
SCHEMBL7443903 0.78 KMT2A (0.51) GRM4ALDH1A1KMT2AMEN1LMNA
SCHEMBL30345246 0.78 GRM4 (0.41) GRM4RAB9ANPC1ALDH1A1KMT2A
SCHEMBL17796977 0.78 KMT2A (0.43) GRM4RAB9ANPC1ALDH1A1KMT2A
SCHEMBL57099 0.77 GRM4 (0.44) GRM4RAB9ANPC1ALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-RE29523-E Olefinic polymers stabilized with thioacyl trivalent phosphorus compounds BORG-WARNER CORPORATION (US) 1978-01-24 US disclosed