SCHEMBL57099

SCHEMBL57099

O=C(Oc1ccccc1Br)Oc1ccccc1Br

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRM4 Q14833 3/20 0.44
KDM4E B2RXH2 3/20 0.42
HPGD P15428 3/20 0.42
HSD17B10 Q99714 1/20 0.42
KMT2A Q03164 5/20 0.41
RAB9A P51151 3/20 0.41
MAPT P10636 3/20 0.41
NPC1 O15118 2/20 0.41
USP2 O75604 1/20 0.41
ALDH1A1 P00352 3/20 0.41
MEN1 O00255 3/20 0.40
LMNA P02545 3/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
MAPK1 P28482 1/20 0.40
HTT P42858 1/20 0.40
LY96 Q9Y6Y9 1/20 0.40
HTR7 P34969 1/20 0.38
GAA P10253 1/20 0.38
STAT3 P40763 1/20 0.38
STAT1 P42224 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29549932 1.00 GRM4 (0.44) GRM4KDM4EHPGDHSD17B10KMT2A
SCHEMBL5704392 0.90 ALDH1A1 (0.42) GRM4KDM4EHPGDHSD17B10KMT2A
SCHEMBL9577110 0.88 PTK2B (0.44) GRM4HPGDKMT2AMAPTMEN1
SCHEMBL9064777 0.88 GRM4 (0.38) GRM4KDM4EHPGDHSD17B10KMT2A
SCHEMBL6255840 0.88 PTK2B (0.44) GRM4HPGDKMT2AMAPTMEN1
SCHEMBL26667034 0.87 HSD17B10 (0.59) GRM4KDM4EHPGDHSD17B10KMT2A
SCHEMBL11013322 0.87 LMNA (0.42) GRM4KDM4EHPGDHSD17B10KMT2A
SCHEMBL6959141 0.84 GRM4 (0.43) GRM4KDM4EHPGDKMT2ARAB9A
SCHEMBL57100 0.84 KMT2A (0.44) GRM4KDM4EHPGDHSD17B10KMT2A
SCHEMBL1638840 0.83 ALDH1A1 (0.40) GRM4KDM4EHPGDHSD17B10KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 996 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1572728-B1 POLYMER CONJUGATES WITH DECREASED ANTIGENICITY, METHODS OF PREPARATION AND USES THEREOF MOUNTAIN VIEW PHARMACEUTICALS (US) 2014-06-25 EP claimed
US-20120114742-A1 Polymer Conjugates with Decreased Antigenicity, Methods of Preparation and Uses Thereof MOUNTAIN VIEW PHARMACEUTICALS, INC. (US) 2012-05-10 US claimed
US-8129330-B2 Complex of polyoxyethylene glycol with active material MOUNTAIN VIEW PHARMACEUTICALS, INC. (US) 2012-03-06 US claimed
JP-2006510601-A 2006-03-30 JP claimed
EP-1572728-A2 POLYMER CONJUGATES WITH DECREASED ANTIGENICITY, METHODS OF PREPARATION AND USES THEREOF Mountain View Pharmaceuticals, Inc. (US) 2005-09-14 EP claimed
EP-1421175-A4 POLYMER STABILIZED PROTEINASES MOUNTAIN VIEW PHARMACEUTICALS (US) 2004-12-08 EP claimed
EP-1421175-A2 POLYMER STABILIZED PROTEINASES Mountain View Pharmaceuticals, Inc. (US) 2004-05-26 EP claimed
WO-2004030617-A2 POLYMER CONJUGATES WITH DECREASED ANTIGENICITY, METHODS OF PREPARATION AND USES THEREOF MOUNTAIN VIEW PHARMACEUTICALS, INC. (US) 2004-04-15 WO claimed
US-20040062748-A1 Polymer conjugates with decreased antigenicity, methods of preparation and uses thereof MOUNTAIN VIEW PHARMACEUTICALS, INC. 2004-04-01 US claimed
US-20040062746-A1 Polymer conjugates with decreased antigenicity, methods of preparation and uses thereof MOUNTAIN VIEW PHARMACEUTICALS, INC. 2004-04-01 US claimed
US-20030012777-A1 Polymer conjugates of proteinases MOUNTAIN VIEW PHARMACEUTICALS, INC. 2003-01-16 US claimed
WO-2003002716-A2 POLYMER STABILIZED PROTEINASES MOUNTAIN VIEW PHARMACEUTICALS, INC. (US) 2003-01-09 WO claimed
CN-122095024-A Flame-retardant aromatic polycarbonate resin composition and molded article thereof 2026-05-26 CN disclosed
WO-2026100296-A1 FLAME-RETARDANT AROMATIC POLYCARBONATE RESIN MASTER BATCH AND METHOD FOR MANUFACTURING SAME 信越化学工業株式会社 2026-05-15 WO disclosed
US-20260001986-A1 THERMOPLASTIC COMPOSITION FOR LASER DIRECT STRUCTURING MCE TECHNICAL CENTER B V (NL) 2026-01-01 US disclosed
EP-4551652-A1 THERMOPLASTIC COMPOSITION FOR LASER DIRECT STRUCTURING MCE Technical Center B.V. (NL) 2025-05-14 EP disclosed
US-4001175-A ADDITIVES OF METAL SALTS OF SULFONIC ACIDS OF AROMATIC SULFOXIDES GENERAL ELECTRIC COMPANY (US) 1977-01-04 US disclosed
US-3971756-A SILOXANE, ORGANIC ALKALI OR ALKALINE EARTH SALTS GENERAL ELECTRIC COMPANY (US) 1976-07-27 US disclosed
US-3945967-A ALKYL PHOSPHITE, EPOXY COMPOUND GENERAL ELECTRIC COMPANY (US) 1976-03-23 US disclosed
US-3933730-A POLYDIMETHYLSILOXANE GUM, DIVIDED SILICA GENERAL ELECTRIC COMPANY (US) 1976-01-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040062748-A1 Polymer conjugates with decreased antigenicity, methods of preparation and uses thereof CD14, HLA-C, HLA-A GRM4 3760/4885KDM4E 1796/4885HPGD 2377/4885
US-20040062746-A1 Polymer conjugates with decreased antigenicity, methods of preparation and uses thereof CD14, HLA-C, HLA-A GRM4 3760/4885KDM4E 1796/4885HPGD 2377/4885
US-20260001986-A1 THERMOPLASTIC COMPOSITION FOR LASER DIRECT STRUCTURING DYNLL2, PUM2, DYNLL1 GRM4 477/4885KDM4E 1855/4885HPGD 4803/4885
US-20120114742-A1 Polymer Conjugates with Decreased Antigenicity, Methods of Preparation and Uses Thereof CD14, HLA-C, HLA-A GRM4 3760/4885KDM4E 1796/4885HPGD 2377/4885
US-20030012777-A1 Polymer conjugates of proteinases PRNP, PRSS3, PRSS1 GRM4 3590/4885KDM4E 2259/4885HPGD 1919/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.