Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.55 |
| ▸ | DRD1 | P21728 | 1/20 | 0.55 |
| ▸ | DRD3 | P35462 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
| ▸ | BIRC5 | O15392 | 1/20 | 0.49 |
| ▸ | HTR1B | P28222 | 2/20 | 0.48 |
| ▸ | HTR1D | P28221 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11600037 | 0.92 | ALDH1A1 (0.60) | DRD2DRD1DRD3ALDH1A1KDM4E | |
| SCHEMBL9706154 | 0.88 | DRD3 (0.67) | DRD2DRD1DRD3ALDH1A1KDM4E | |
| SCHEMBL11599606 | 0.81 | LTA4H (0.50) | ALDH1A1KDM4ELTA4HMCHR1 | |
| Guaiactamine SCHEMBL25797 | 0.81 | ALDH1A1 (0.78) | DRD2DRD1DRD3ALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL11601902 | 0.80 | LTA4H (0.49) | ALDH1A1KDM4ELTA4HMCHR1 | |
| SCHEMBL12413483 | 0.80 | DRD2 (0.55) | DRD2DRD1DRD3ALDH1A1KDM4E | |
| SCHEMBL4334443 | 0.80 | ALDH1A1 (0.55) | ALDH1A1KDM4ELMNATSHRCYP1A2 | |
| SCHEMBL7931093 | 0.79 | CYP1A2 (0.56) | ALDH1A1LMNACYP1A2CYP2D6LTA4H | |
| SCHEMBL28428684 | 0.77 | DRD3 (0.59) | DRD2DRD1DRD3ALDH1A1KDM4E | |
| SCHEMBL8360708 | 0.77 | DRD2 (0.64) | DRD2DRD1DRD3ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4073917-A | Local anesthetics tertiary aminoalkoxyphenyl ethers | ASTRA LAKEMEDEL AKTIEBOLAG (SW) | 1978-02-14 | — | — | US | claimed |
| US-4073917-A | Local anesthetics tertiary aminoalkoxyphenyl ethers | ASTRA LAKEMEDEL AKTIEBOLAG (SW) | 1978-02-14 | — | — | US | disclosed |