SCHEMBL11599993

SCHEMBL11599993

CC(N)C(=O)n1ccnc1

nearest known ligand 0.55

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SMYD3 Q9H7B4 1/20 0.38
TBXAS1 P24557 2/20 0.35
FAAH O00519 1/20 0.35
MGLL Q99685 1/20 0.35
ALDH1A1 P00352 2/20 0.34
NFKB1 P19838 1/20 0.33
QPCT Q16769 1/20 0.33
HSD17B10 Q99714 1/20 0.33
QPCTL Q9NXS2 1/20 0.33
AAK1 Q2M2I8 1/20 0.33
LMNA P02545 1/20 0.33
CYP24A1 Q07973 1/20 0.33
MAPT P10636 1/20 0.33
CYP3A4 P08684 1/20 0.33
BAZ2B Q9UIF8 1/20 0.33
EGLN3 Q9H6Z9 1/20 0.32
AHR P35869 1/20 0.32
KDM4E B2RXH2 1/20 0.32
FABP4 P15090 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8532374 1.00 SMYD3 (0.38) SMYD3TBXAS1FAAHMGLLALDH1A1
SCHEMBL2143878 0.83 TBXAS1 (0.37) TBXAS1FAAHMGLLALDH1A1NFKB1
SCHEMBL28007639 0.81 SMYD3 (0.34) SMYD3TBXAS1FAAHMGLLALDH1A1
SCHEMBL28882573 0.80 TBXAS1 (0.35) TBXAS1FAAHMGLLALDH1A1NFKB1
SCHEMBL424444 0.78 ALDH1A1 (0.37) TBXAS1FAAHMGLLALDH1A1MAPT
SCHEMBL18775172 0.77 TBXAS1 (0.40) TBXAS1FAAHMGLLALDH1A1LMNA
SCHEMBL971489 0.77 TBXAS1 (0.35) TBXAS1FAAHMGLLALDH1A1AAK1
SCHEMBL13587345 0.77 TBXAS1 (0.40) TBXAS1FAAHMGLLALDH1A1LMNA
Isopropyl Alcohol SCHEMBL17780187 0.76 TBXAS1 (0.35) TBXAS1FAAHMGLLALDH1A1NFKB1
Bromide SCHEMBL28706700 0.76 CYP19A1 (0.37) NFKB1QPCTHSD17B10QPCTL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4081509-A Method for removing nitrogen oxides from flue gas by absorption HITACHI, LTD. (JA) 1978-03-28 US disclosed