Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | TBXAS1 | P24557 | 9/20 | 0.36 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | FDPS | P14324 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HMOX2 | P30519 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11599993 | 0.78 | SMYD3 (0.38) | ALDH1A1TBXAS1EGLN3FAAHMGLL | |
| SCHEMBL8532374 | 0.78 | SMYD3 (0.38) | ALDH1A1TBXAS1EGLN3FAAHMGLL | |
| SCHEMBL28044667 | 0.78 | GSR (0.46) | TBXAS1 | |
| SCHEMBL9201894 | 0.75 | TBXAS1 (0.33) | ALDH1A1TBXAS1EGLN3FAAHMGLL | |
| SCHEMBL13448304 | 0.75 | HTT (0.36) | ALDH1A1TBXAS1EGLN3FAAHMGLL | |
| SCHEMBL28770447 | 0.74 | PDE4A (0.43) | ALDH1A1TBXAS1EGLN3FAAHMGLL | |
| SCHEMBL7780136 | 0.74 | ALDH1A1 (0.36) | ALDH1A1TBXAS1EGLN3FAAHMGLL | |
| SCHEMBL2143878 | 0.74 | TBXAS1 (0.37) | ALDH1A1TBXAS1EGLN3FAAHMGLL | |
| SCHEMBL29240433 | 0.73 | SLC1A1 (0.32) | — | |
| SCHEMBL2577040 | 0.72 | TSHR (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170114014-A1 | B-LACTAM COMPOUNDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-04-27 | — | — | US | disclosed |
| US-9469610-B2 | β-lactam compounds | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2016-10-18 | — | — | US | disclosed |
| US-8946408-B2 | Method for synthesizing beta lactam compounds by decomposition of an alpha-diazo-beta-ketoamide using a fluorescent light source | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2015-02-03 | — | — | US | disclosed |
| US-20120184731-A1 | Method for synthesizing beta lactam compounds by decomposition of an alpha-diazo-beta-ketoamide using a fluorescent light source | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2012-07-19 | — | — | US | disclosed |
| US-20120022248-A1 | B-LACTAM COMPOUNDS | The Regents of the University of Technology Office of Technology Transfer (US) | 2012-01-26 | — | — | US | disclosed |
| WO-2011115613-A1 | A METHOD FOR SYNTHESIZING BETA-LACTAM COMPOUNDS BY DECOMPOSITION OF AN ALPHA-DIAZO-BETA-KETOAMIDE USING A FLUORESCENT LIGHT SOURCE | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2011-09-22 | — | — | WO | disclosed |
| WO-2010105267-A2 | β-LACTAM COMPOUNDS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-09-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120022248-A1 | B-LACTAM COMPOUNDS | COASY, BBOX1, GNE | ALDH1A1 2472/4885TBXAS1 751/4885EGLN3 1502/4885 |
| US-20120184731-A1 | Method for synthesizing beta lactam compounds by decomposition of an alpha-diazo-beta-ketoamide using a fluorescent light source | PTMA, GLA, GLB1 | ALDH1A1 937/4885TBXAS1 1089/4885EGLN3 637/4885 |
| US-20170114014-A1 | B-LACTAM COMPOUNDS | COASY, BBOX1, GNE | ALDH1A1 2472/4885TBXAS1 751/4885EGLN3 1502/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.