Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 1/20 | 0.45 |
| ▸ | FNTB | P49356 | 1/20 | 0.45 |
| ▸ | PTAFR | P25105 | 3/20 | 0.41 |
| ▸ | DRD3 | P35462 | 5/20 | 0.40 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.39 |
| ▸ | SETD7 | Q8WTS6 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.36 |
| ▸ | DRD1 | P21728 | 3/20 | 0.36 |
| ▸ | HRH1 | P35367 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11600654 | 0.90 | FNTA (0.54) | FNTAFNTBPTAFRDRD3DRD2 | |
| SCHEMBL11602160 | 0.90 | FNTA (0.44) | FNTAFNTBPTAFRDRD3DRD2 | |
| SCHEMBL11601081 | 0.88 | FNTA (0.43) | FNTAFNTBPTAFRDRD3DRD2 | |
| SCHEMBL11599742 | 0.84 | FNTA (0.56) | FNTAFNTBPTAFRDRD3DRD2 | |
| Acetic Acid SCHEMBL7681832 | 0.82 | FNTA (0.52) | FNTAFNTBPTAFRDRD3DRD2 | |
| SCHEMBL11602373 | 0.82 | FNTA (0.44) | FNTAFNTBPTAFRDRD3DRD2 | |
| SCHEMBL11601198 | 0.82 | KCNH2 (0.49) | PTAFRDRD3DRD2SETD7KCNH2 | |
| SCHEMBL11599673 | 0.81 | PTAFR (0.60) | FNTAFNTBPTAFRDRD3DRD2 | |
| SCHEMBL7676763 | 0.81 | FNTA (0.55) | FNTAFNTBPTAFRDRD3DRD2 | |
| SCHEMBL7681833 | 0.80 | FNTA (0.51) | FNTAFNTBPTAFRDRD3DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4072756-A | Tricyclo piperidino ketones and soporific compositions thereof | SANDOZ LTD. (CH) | 1978-02-07 | — | — | US | disclosed |