Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | PTAFR | P25105 | 2/20 | 0.41 |
| ▸ | DRD3 | P35462 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | SETD7 | Q8WTS6 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11601728 | 0.90 | KCNH2 (0.53) | KCNH2PTAFRDRD3DRD2TP53 | |
| SCHEMBL11600950 | 0.89 | KCNH2 (0.46) | KCNH2PTAFRDRD3DRD2 | |
| SCHEMBL11602913 | 0.88 | ALDH1A1 (0.49) | KCNH2PTAFRDRD3DRD2KMT2A | |
| SCHEMBL11600344 | 0.83 | KCNH2 (0.55) | KCNH2PTAFRDRD3DRD2MEN1 | |
| SCHEMBL11599673 | 0.82 | PTAFR (0.60) | KCNH2PTAFRDRD3DRD2MEN1 | |
| SCHEMBL3131282 | 0.82 | SETD7 (0.57) | KCNH2PTAFRDRD3DRD2MEN1 | |
| SCHEMBL11600538 | 0.82 | KCNH2 (0.46) | KCNH2PTAFRDRD3DRD2MEN1 | |
| SCHEMBL11600227 | 0.82 | FNTA (0.45) | KCNH2PTAFRDRD3DRD2MEN1 | |
| SCHEMBL11602831 | 0.81 | SETD7 (0.51) | KCNH2PTAFRDRD2MEN1KMT2A | |
| SCHEMBL9718719 | 0.80 | KCNH2 (0.54) | KCNH2PTAFRDRD3DRD2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4072756-A | Tricyclo piperidino ketones and soporific compositions thereof | SANDOZ LTD. (CH) | 1978-02-07 | — | — | US | disclosed |