Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 2/20 | 0.43 |
| ▸ | FNTB | P49356 | 2/20 | 0.43 |
| ▸ | DRD3 | P35462 | 5/20 | 0.43 |
| ▸ | DRD2 | P14416 | 3/20 | 0.43 |
| ▸ | HRH1 | P35367 | 2/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.42 |
| ▸ | PTAFR | P25105 | 2/20 | 0.41 |
| ▸ | RYR2 | Q92736 | 2/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11600227 | 0.88 | FNTA (0.45) | FNTAFNTBDRD3DRD2HRH1 | |
| SCHEMBL11600654 | 0.88 | FNTA (0.54) | FNTAFNTBDRD3DRD2HRH1 | |
| SCHEMBL11602160 | 0.87 | FNTA (0.44) | FNTAFNTBDRD3DRD2HRH1 | |
| SCHEMBL11602913 | 0.83 | ALDH1A1 (0.49) | FNTAFNTBDRD3DRD2HRH1 | |
| SCHEMBL11599742 | 0.81 | FNTA (0.56) | FNTAFNTBDRD3DRD2HRH1 | |
| SCHEMBL11601639 | 0.81 | PTAFR (0.50) | FNTAFNTBDRD3DRD2HRH1 | |
| SCHEMBL7681833 | 0.80 | FNTA (0.51) | FNTAFNTBDRD3DRD2HRH1 | |
| Acetic Acid SCHEMBL7681832 | 0.80 | FNTA (0.52) | FNTAFNTBDRD3DRD2HRH1 | |
| SCHEMBL11602373 | 0.80 | FNTA (0.44) | FNTAFNTBDRD3DRD2HRH1 | |
| SCHEMBL11599673 | 0.79 | PTAFR (0.60) | FNTAFNTBDRD3DRD2HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4072756-A | Tricyclo piperidino ketones and soporific compositions thereof | SANDOZ LTD. (CH) | 1978-02-07 | — | — | US | disclosed |