Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | PTAFR | P25105 | 2/20 | 0.49 |
| ▸ | DRD3 | P35462 | 6/20 | 0.46 |
| ▸ | HRH1 | P35367 | 5/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.46 |
| ▸ | DRD2 | P14416 | 4/20 | 0.46 |
| ▸ | HTR2A | P28223 | 4/20 | 0.46 |
| ▸ | HTR2C | P28335 | 4/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 4/20 | 0.46 |
| ▸ | DRD1 | P21728 | 4/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | ADRA2B | P18089 | 3/20 | 0.46 |
| ▸ | HTR3A | P46098 | 3/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11600894 | 0.87 | PTAFR (0.63) | MAPK1MEN1MAPTKMT2APTAFR | |
| SCHEMBL11601745 | 0.84 | MAPK1 (0.69) | MAPK1MEN1MAPTKMT2APTAFR | |
| SCHEMBL11600303 | 0.83 | PTAFR (0.46) | MAPK1MEN1MAPTKMT2APTAFR | |
| SCHEMBL11601694 | 0.80 | PTAFR (0.52) | PTAFRHRH1KCNH2SETD7FNTA | |
| SCHEMBL11600653 | 0.80 | PTAFR (0.52) | MAPK1MEN1MAPTKMT2APTAFR | |
| SCHEMBL11599673 | 0.80 | PTAFR (0.60) | MAPK1MEN1MAPTKMT2APTAFR | |
| SCHEMBL3787169 | 0.79 | CYP2D6 (0.47) | MAPK1MEN1MAPTKMT2APTAFR | |
| SCHEMBL11602084 | 0.78 | DRD3 (0.65) | MAPK1MEN1MAPTKMT2APTAFR | |
| SCHEMBL11602883 | 0.78 | PTAFR (0.50) | MAPK1MEN1MAPTKMT2APTAFR | |
| SCHEMBL11601639 | 0.78 | PTAFR (0.50) | MAPK1MEN1MAPTKMT2APTAFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4072756-A | Tricyclo piperidino ketones and soporific compositions thereof | SANDOZ LTD. (CH) | 1978-02-07 | — | — | US | disclosed |