Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 4/20 | 0.52 |
| ▸ | HRH1 | P35367 | 14/20 | 0.52 |
| ▸ | SLC6A15 | Q9H2J7 | 5/20 | 0.52 |
| ▸ | FNTA | P49354 | 2/20 | 0.52 |
| ▸ | FNTB | P49356 | 2/20 | 0.52 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11600894 | 0.89 | PTAFR (0.63) | PTAFRHRH1FNTAFNTBSETD7 | |
| SCHEMBL11602383 | 0.86 | FNTA (0.49) | PTAFRHRH1SLC6A15FNTAFNTB | |
| SCHEMBL11602054 | 0.83 | SETD7 (0.50) | PTAFRHRH1SLC6A15FNTAFNTB | |
| SCHEMBL11600653 | 0.82 | PTAFR (0.52) | PTAFRHRH1FNTAFNTBSETD7 | |
| SCHEMBL11599673 | 0.82 | PTAFR (0.60) | PTAFRHRH1FNTAFNTBSETD7 | |
| SCHEMBL11599600 | 0.81 | SETD7 (0.52) | PTAFRHRH1FNTAFNTBSETD7 | |
| SCHEMBL11600718 | 0.81 | SETD7 (0.50) | PTAFRHRH1SETD7KCNH2 | |
| SCHEMBL11602883 | 0.81 | PTAFR (0.50) | PTAFRHRH1FNTAFNTBSETD7 | |
| SCHEMBL11601639 | 0.81 | PTAFR (0.50) | PTAFRHRH1FNTAFNTBSETD7 | |
| SCHEMBL11602839 | 0.81 | PTAFR (0.50) | PTAFRHRH1FNTAFNTBSETD7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4072756-A | Tricyclo piperidino ketones and soporific compositions thereof | SANDOZ LTD. (CH) | 1978-02-07 | — | — | US | disclosed |