Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR | P25105 | 3/20 | 0.50 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | FNTA | P49354 | 1/20 | 0.40 |
| ▸ | FNTB | P49356 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 4/20 | 0.40 |
| ▸ | DRD3 | P35462 | 4/20 | 0.40 |
| ▸ | HRH1 | P35367 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.40 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | HTR2C | P28335 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11601086 | 0.88 | SETD7 (0.49) | PTAFRSETD7MAPK1MEN1MAPT | |
| SCHEMBL11600894 | 0.88 | PTAFR (0.63) | PTAFRSETD7MAPK1MEN1MAPT | |
| SCHEMBL11600653 | 0.87 | PTAFR (0.52) | PTAFRSETD7MAPK1MEN1MAPT | |
| SCHEMBL11602839 | 0.83 | PTAFR (0.50) | PTAFRSETD7MAPK1MEN1MAPT | |
| SCHEMBL11601639 | 0.83 | PTAFR (0.50) | PTAFRSETD7MAPK1MEN1MAPT | |
| SCHEMBL11601694 | 0.81 | PTAFR (0.52) | PTAFRSETD7KCNH2FNTAFNTB | |
| SCHEMBL11599673 | 0.81 | PTAFR (0.60) | PTAFRSETD7MAPK1MEN1MAPT | |
| SCHEMBL11601745 | 0.78 | MAPK1 (0.69) | PTAFRSETD7MAPK1MEN1MAPT | |
| SCHEMBL11600359 | 0.78 | MAPK1 (0.49) | PTAFRSETD7MAPK1MEN1MAPT | |
| SCHEMBL9718792 | 0.76 | SETD7 (0.58) | PTAFRSETD7MAPK1MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4072756-A | Tricyclo piperidino ketones and soporific compositions thereof | SANDOZ LTD. (CH) | 1978-02-07 | — | — | US | disclosed |