Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.51 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11598499 | 1.00 | ALDH1A1 (0.51) | ALDH1A1CYP3A4ALOX15TSHRHSD17B10 | |
| SCHEMBL11598302 | 0.85 | LMNA (0.40) | ALDH1A1ALOX12MAPK1MAPTSMN1; SMN2 | |
| SCHEMBL11600611 | 0.85 | LMNA (0.40) | ALDH1A1ALOX12MAPK1MAPTSMN1; SMN2 | |
| SCHEMBL9020975 | 0.82 | LMNA (0.37) | ALDH1A1CYP3A4ALOX15TSHRHSD17B10 | |
| SCHEMBL11600626 | 0.82 | ALDH1A1 (0.49) | ALDH1A1CYP3A4ALOX15TSHRHSD17B10 | |
| SCHEMBL11598498 | 0.82 | ALDH1A1 (0.49) | ALDH1A1CYP3A4ALOX15TSHRHSD17B10 | |
| SCHEMBL9933293 | 0.75 | ALDH1A1 (0.85) | ALDH1A1CYP3A4ALOX15TSHRHSD17B10 | |
| SCHEMBL29388293 | 0.75 | ESR1 (0.42) | ALDH1A1CYP3A4HSD17B10HIF1AMAPT | |
| SCHEMBL6075249 | 0.75 | ESR1 (0.42) | ALDH1A1CYP3A4HSD17B10HIF1AMAPT | |
| SCHEMBL8691921 | 0.75 | ALDH1A1 (0.72) | ALDH1A1CYP3A4ALOX15TSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4124565-A | STABILIZERS, ANTIOXIDANTS, ANTIOZONANTS | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1978-11-07 | — | — | US | disclosed |